ArticleRenal failure2025
The association between nutritional-inflammatory status and chronic kidney disease prognosis: a population-based study.
Article in Renal failure, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it.
- CONUT Score as a Predictor of Mortality Risk in Acute and Chronic Heart Failure: A Meta-Analytic Review.Nutrients · 2025Pooled it
- An Inflammation-Adjusted Framework for Nutritional Assessment in Multimorbid Patients with Advanced Neurological Diseases.Medicina (Kaunas, Lithuania) · 2026Observational
- Prognostic Value of the CONUT Score in Predicting All-Cause Mortality in Hospitalized Internal Medicine Patients: A Retrospective Cohort Study.Journal of clinical medicine · 2026Article
- Advanced lung cancer inflammation index and mortality risk in patients with cardiovascular disease.BMC cardiovascular disorders · 2026Article
- Article
- Letter to the editor regarding 'the association between nutritional-inflammatory status and chronic kidney disease prognosis: a population-based study'.Renal failure · 2025Article
- Malnutrition in Elderly Patients with Chronic Kidney Disease-The Role of Albuminuria.Life (Basel, Switzerland) · 2025Article
- Advanced lung cancer inflammation index is associated with mortality in critically ill patients with non-traumatic cerebral hemorrhage.Scientific reports · 2025Article
- Establishment and Validation of a Novel Nutritional-Immune-Inflammatory Score Model for Predicting Survival Prognosis in Hepatocellular Carcinoma Patients Treated with PD-1 Inhibitors.Journal of inflammation research · 2025Article
- Association between objective nutritional indices and malnutrition inflammation score in peritoneal dialysis patients.Frontiers in nutrition · 2025Article
- Biochemical indicators, physical activity, and functional performance in elderly CKD patients: A cross-sectional study.Science progressArticle
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundChronic kidney disease (CKD) prognosis is closely tied to the interplay between nutrition and inflammation. However, comprehensive nutritional-inflammatory indices for prognostic evaluation are rare in CKD. This study explored the association of the advanced lung cancer inflammation index (ALI) with estimated glomerular filtration rate (eGFR) and all-cause mortality in CKD patients.
methodsA total of 1,982 CKD patients from the National Health and Nutrition Examination Survey (NHANES) database (2011
resultsAmong CKD patients, 1,103 patients (55.7%) were classified as stage I-II, and 879 patients (44.3%) as stage III-V. After adjusting covariates, ALI was found to be positively correlated with eGFR (Beta = 0.11; 95% CI: 0.07-0.15), and negatively related with all-cause mortality (HR = 0.72; 95% CI: 0.63-0.83). Subgroup analysis showed that the positive correlation between ALI and eGFR was stronger in CKD stage III-V compared to stage I-II. However, ALI's protective effect on mortality was weaker in stage III-V. The C-index for ALI was 0.648 in stage I-II and 0.660 in stage III-V.
conclusionALI was significantly associated with eGFR and all-cause mortality in CKD patients. Nutritional and anti-inflammatory interventions in early-stage CKD may improve prognosis, and ALI may have great potential as a multifaceted biomarker to influence the prognosis of CKD, particularly in stages III-V.
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