Evidence map›Paper›PMID 40082882›Full record

ArticleJournal of orthopaedic surgery and research2025

Research on the biomechanical characteristics of the tibiofemoral joint before and after kinematic alignment unicompartmental knee arthroplasty.

Chong Li, Mengyu Chen, XiangYing Wang, SongHua Yan, Kuan Zhang, Ji Zhou Zeng

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Article in Journal of orthopaedic surgery and research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Chong LiDepartment of Bone and Joint Surgery, Beijing Luhe Hospital, Capital Medical University, 82# Xinhua South Road, Tongzhou District, Beijing, 101149, People's Republic of China.
Mengyu ChenDepartment of Bone and Joint Surgery, Beijing Luhe Hospital, Capital Medical University, 82# Xinhua South Road, Tongzhou District, Beijing, 101149, People's Republic of China.
XiangYing WangDepartment of Orthopedic Oncology Surgery, Shandong Cancer Hospital and Institute, Shandong First Medical University, Shandong Academy of Medical Science, 440# Jinyan Road, Huaiyin District, Jinan, 250117, People's Republic of China.
SongHua YanSchool of Biomedical Engineering, Capital Medical University, 10#Xitoutiao, You An Men Wai, Fengtai District, Beijing, 100069, People's Republic of China.
Kuan ZhangSchool of Biomedical Engineering, Capital Medical University, 10#Xitoutiao, You An Men Wai, Fengtai District, Beijing, 100069, People's Republic of China. kzhang@ccmu.edu.cn.
Ji Zhou ZengDepartment of Bone and Joint Surgery, Beijing Luhe Hospital, Capital Medical University, 82# Xinhua South Road, Tongzhou District, Beijing, 101149, People's Republic of China. zeng@ccmu.edu.cn.

Funding

Beijing Key Laboratory of Fundamental Research on Biomechanics in Clinical Application, Capital Medical University, Beijing, China 2023KF03Tongzhou district science & technology foundation,Beijing, China KJ2023SS001
6 · The paper itself

Abstract

backgroundKinematic alignment (KA) unicompartmental knee arthroplasty (UKA), which has not been widely adopted in clinical practice, aims to implant a more personalized and physiologically compatible mobile-bearing UKA prosthesis for the treatment of advanced single compartment knee osteoarthritis. KA UKA is anticipated to enhance patient satisfaction and decrease the revision rate following UKA. However, its quantified biomechanical indicators remain unclear. The purpose of this study is to reveal the biomechanical characteristics of the tibiofemoral joint in normal and KA UKA knees, and to evaluate the biomechanical effect.

methodsIn this study, six cadaveric knee joint specimens were utilized for biomechanical testing before (normal cadaveric knee joint specimen ) and after KA UKA. The knee joint specimens were subjected to an axial load of 1000 N, and the biomechanical parameters were assessed at flexion angles ranging from 0° to 120° in 10° increments.

resultsThe root mean square (RMS) values of the tibiofemoral contact area, mean contact pressure, and peak contact pressure during knee flexion were 529 mm², 1.8 MPa, and 4.5 MPa in normal knees, respectively. After KA UKA, these values changed to 449 mm², 2.0 MPa, and 9.8 MPa, respectively. Additionally, the RMS value of the external rotation of the femur relative to the tibia in the tibiofemoral joint was 9.9° in normal knees, while the posterior translations of the center of the femoral condyle, the medial femoral condyle, and the lateral femoral condyle were 18.4 mm, 11.5 mm, and 25.4 mm respectively. After KA UKA, these values changed to 8.6°, 19.3 mm, 12.9 mm, and 25.9 mm respectively.

conclusionAt the same flexion angle, the increase in peak contact pressure in the medial compartment after KA UKA is the most significant compared with the normal knees. However, the kinematic characteristics do not change significantly after KA UKA. These findings are beneficial for understanding the possible postoperative complications and good functional effects of KA UKA.

Indexed as

Arthroplasty, Replacement, KneeFemurKnee JointTibiaAgedAged, 80 and overBiomechanical PhenomenaCadaverFemaleHumansKnee ProsthesisMaleMiddle AgedRange of Motion, ArticularTibiofemoral JointBiomechanical testingCadaveric knee specimenKinematic alignmentTibiofemoral jointUnicompartmental knee arthroplasty

Identifiers

PMID40082882
PMCPMC11908032

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.