Evidence map›Paper›PMID 40082824›Full record

ArticleBMC psychiatry2025

Personality perspective on depression and anxiety symptoms among Chinese adolescents and young adults: a two-sample network analysis.

Xian-Yang Wang, Zi-Wei Wang, Dong-Lei Jiang, Chang Liu, Wan-Ying Xing, Zhi-Tao Yuan, Long-Biao Cui, Sheng-Jun Wu, Lei Ren

Abstract read
In one paragraph

Article in BMC psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Xian-Yang Wang *Department of Military Medical Psychology, The Fourth Military Medical University, 169 West Changle Road, Xi'an, Shaanxi, 710032, China.
Zi-Wei Wang *Department of Military Medical Psychology, The Fourth Military Medical University, 169 West Changle Road, Xi'an, Shaanxi, 710032, China.
Dong-Lei Jiang *School of Basic Medicine, The Fourth Military Medical University, Xi'an, Shaanxi, 710032, China.
Chang LiuBrain Park, School of Psychological Sciences, Turner Institute for Brain and Mental Health, Monash University, Clayton, VIC, 3800, Australia.
Wan-Ying XingDepartment of Military Medical Psychology, The Fourth Military Medical University, 169 West Changle Road, Xi'an, Shaanxi, 710032, China.
Zhi-Tao YuanDepartment of Military Medical Psychology, The Fourth Military Medical University, 169 West Changle Road, Xi'an, Shaanxi, 710032, China.
Long-Biao CuiShaanxi Provincial Key Laboratory of Clinic Genetics, The Fourth Military Medical University, Xi'an, Shaanxi, 710032, China.
Sheng-Jun WuDepartment of Military Medical Psychology, The Fourth Military Medical University, 169 West Changle Road, Xi'an, Shaanxi, 710032, China. wushj@fmmu.edu.cn.
Lei RenMilitary Psychology Section, Logistics University of PAP, 1 Huizhihuan Road, Tianjin, 300309, China. rl_fmmu@163.com.

Funding

National Natural Science Foundation of China 72374208
6 · The paper itself

Abstract

backgroundThe mental health burden among adolescents has been increasing, impacting individuals even before formal diagnosis of common mental disorders. Although personality traits, as key indicators of mental health conditions, play a crucial role in the development of mental disorders, there is a gap regarding the trait-to-symptom pathways and similarities and differences between adolescents and young adults.

methodsA total of 860 adolescents and 1751 young adults participated in this study. The Chinese Big Five Personality Inventory assessed the Big Five traits, while depression and anxiety symptoms were measured using the Patient Health Questionnaire-9 and the Generalized Anxiety Disorder-7, respectively. Network analysis computed the bridging centrality of Big Five traits and elucidated trait-to-symptom pathways. Furthermore, network comparison was applied to compare network structure between adolescents and young adults.

resultsIn both age groups, neuroticism exhibited a transdiagnostic activating effect on depression and anxiety. Conscientiousness demonstrated the strongest protective effect against depression, whereas agreeableness was most protective against anxiety. In both samples, neuroticism primarily influenced symptoms associated with negative emotions and thoughts. Comparatively, extraversion exhibited a significant increasing protective effect against depression throughout adolescence, while neuroticism increasingly activated anxiety symptoms.

conclusionsThis study highlights the potential to utilize personality traits for early detection and precise intervention in adolescent populations, providing actionable insights. By identifying the level of neuroticism, we can effectively detect high-risk adolescent individuals prior to formal diagnosis. By delineating the neuroticism-to-symptom pathways, we can implement targeted intervention on their pathological interactions.

Indexed as

AnxietyDepressionPersonalityAdolescentAdultChinaEast Asian PeopleFemaleHumansMaleNeuroticismPersonality InventoryYoung AdultAnxietyBig five traitsDepressionNetwork analysis

Identifiers

PMID40082824
PMCPMC11907812

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.