ArticleCommunications medicine2025
Magnetic particle imaging angiography of the femoral artery in a human cadaveric perfusion model.
Article in Communications medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Millisecond magnetic particle imaging of a cerebral aneurysm phantom with and without flow diverter stent.Communications engineering · 2026Article
- Magnetic particle imaging tracers for human applications: preclinical in vivo evaluation of Magtrace, Resotran, and FerroTrace.Npj imaging · 2026Article
- Towards robot-assisted magnetic particle imaging for mobile point-of-care (neuro)vascular applications.Scientific reports · 2026Article
- Whole-body in vivo MPI cytometry reveals injection route-, dose-, cell size-, and disease-dependent differences in organ distribution.Science advances · 2026Article
- Imaging of Artificial Tumor Models in an Anatomical Breast Phantom with a Single-Sided Magnetic Particle Imaging Scanner.Tomography (Ann Arbor, Mich.) · 2026Article
- Magnetic Particle Imaging in Human Subjects.Research square · 2026Article
- Continuous Coagulation Monitoring in Human Blood Samples via Magnetic Particle Spectroscopy.International journal of nanomedicine · 2026Article
- Superparamagnetic iron oxide nanoparticles in clinical applications: current status and future perspectives.EBioMedicine · 2025Review
- Towards clinical magnetic particle imaging: safety measurements of medical implants in a human cadaver model.Communications engineering · 2025Article
- Enhanced performance of a single-sided MPI scanner with a hybrid surface-volume excitation coil.Physics in medicine and biology · 2025Article
- Cardiovascular Imaging Applications, Implementations, and Challenges Using Novel Magnetic Particle Imaging.Bioengineering (Basel, Switzerland) · 2025Review
Corrections and comments
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Authors and funding
15 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMagnetic particle imaging (MPI) allows for radiation-free visualization of tracers without background signal. With the first human-sized interventional MPI scanner being recently developed, the aim of the present study was to test its performance for guiding of endovascular procedures in a realistic perfusion model.
methodsThree fresh-frozen cadaveric legs were prepared to establish continuous circulation in the superficial femoral artery via introducer sheaths in the inguinal and infragenicular region. To facilitate vessel visualization, a mixture of a MPI tracer (Resotran® or Perimag®) and X-ray contrast agent was injected under continuous extracorporeal perfusion and imaged simultaneously with MPI angiography and digital subtraction angiography (DSA) as reference.
resultsThe MPI scanner integrates seamlessly into the standard operating procedures in the angiography suite and simultaneous imaging with DSA and MPI is feasible. The MPI scanner detects a tracer bolus of 2 ml Perimag® or 1.5 ml Resotran®. Imaging results are consistent and reproducible in three cadaveric leg phantoms.
conclusionThis study demonstrates, that the recently developed human-sized MPI scanner facilitates reliable radiation-free image guidance for peripheral vascular interventions in the superficial femoral artery with a tracer approved for use in humans.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.