Evidence map›Paper›PMID 40082693›Full record

ArticleScientific reports2025

Evaluation of the role of thyroid hormones, vitamin B12, vitamin D3, folic acid and ferritin serum levels in pterygium development.

Fatma Sumer, Bayram Kizilkaya, Elif Yildiz, Muhammed Fatih Satilmaz, Abdulfettah Suveys

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Fatma SumerFaculty of Medicine, Department of Ophthalmology, Recep Tayyip Erdogan University, Rize, 53100, Turkey. fatmasumer_@hotmail.com.ORCID http://orcid.org/0000-0002-4146-8190
Bayram KizilkayaDepartment of Internal Medicine, Recep Tayyip Erdogan University Training and Research Hospital, Rize, 53100, Turkey.ORCID http://orcid.org/0000-0003-4508-2516
Elif YildizDepartment of Obstetrics and Gynecology, Istanbul Gaziosmanpasa Training And Research Hospital, Istanbul, 34100, Turkey.ORCID http://orcid.org/0000-0001-8396-5542
Muhammed Fatih SatilmazFaculty of Medicine, Department of Ophthalmology, Recep Tayyip Erdogan University, Rize, 53100, Turkey.ORCID http://orcid.org/0000-0002-0388-4281
Abdulfettah SuveysFaculty of Medicine, Department of Ophthalmology, Recep Tayyip Erdogan University, Rize, 53100, Turkey.ORCID http://orcid.org/0009-0000-5985-3014

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To evaluate the relationship between pterygium and serum thyroid hormone, vitamin B12, vitamin D3, folic acid, and ferritin levels between pterygium patients and control and to assess its correlation with clinical findings. 18-65-year-old 100 pterygium patients and age and sex matched 60 healthy control subjects were included. The peripheric blood sampling results were investigated. Free triiodothyronine (FT3), free thyroxine (FT4), thyroid stimulating hormone (TSH), vitamin B12, vitamin D3, folic acid, and ferritin levels of pterygium and control groups were compared. FT3 level was higher in the patient group compared to the control group, while vitamin B12, vitamin D3, folic acid and ferritin levels were significantly lower in the patient group compared to the control group (p < 0.05) No significant difference was found between the patient and control groups in terms of age, gender and body mass index (BMI) (p = 0.295, p = 0.625, p = 0.547, respectively). This study reports that pterygium patients have lower serum vitamin B12, folic acid, ferritin and vitamin D3 levels than healthy individuals.

Indexed as

CholecalciferolFerritinsFolic AcidPterygiumThyroid HormonesVitamin B 12AdolescentAdultAgedCase-Control StudiesFemaleHumansMaleMiddle AgedYoung AdultCholecalciferolFerritinsFolic AcidThyroid HormonesVitamin B 12FerritinPterygium, folic acidThyroidVitamin B12Vitamin D3

Identifiers

PMID40082693
PMCPMC11906757

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.