Evidence map›Paper›PMID 40082598›Full record

ArticleInternational journal of obesity (2005)2025

Examining the roles of body composition, energy expenditure and substrate metabolism in the control of daily energy intake in adolescents with obesity.

D Thivel, M Hopkins, S Lazzer, C Montaurier, H Moore, B Pereira, J E Blundell, L Isacco, Y Boirie

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Article in International journal of obesity (2005), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

D ThivelLaboratory of the Metabolic Adaptations to Exercise under Physiological and Pathological Conditions (AME2P), Clermont Auvergne University, 63000, Clermont-Ferrand, France. David.thivel@uca.fr.ORCID 0000-0003-4687-3555
M HopkinsSchool of Food Science and Nutrition, Faculty of Environment, University of Leeds, Leeds, LS2 9JT, UK.ORCID 0000-0002-7655-0215
S LazzerDepartment of Medicine, School of Sport Sciences, University of Udine, 33058, Udine, Italy.
C MontaurierClermont Auvergne University, INRAE, Unité de Nutrition Humaine, CRNH Auvergne, Clermont-Ferrand, France.
H MooreLaboratory of the Metabolic Adaptations to Exercise under Physiological and Pathological Conditions (AME2P), Clermont Auvergne University, 63000, Clermont-Ferrand, France.ORCID 0000-0002-0741-245X
B PereiraBiostatistics Unit, DRCI, CHU Clermont-Ferrand, 63000, Clermont-Ferrand, France.ORCID 0000-0003-3778-7161
J E BlundellAppetite and Energy Balance Research Group, School of Psychology, Faculty of Medicine and Health, University of Leeds, Leeds, UK.ORCID 0000-0002-7085-9596
L IsaccoLaboratory of the Metabolic Adaptations to Exercise under Physiological and Pathological Conditions (AME2P), Clermont Auvergne University, 63000, Clermont-Ferrand, France.ORCID 0000-0002-1152-3902
Y BoirieDepartment of Human Nutrition, CHU Clermont-Ferrand, 63000, Clermont-Ferrand, France.ORCID 0000-0002-3999-1599

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe implication of body composition and energy metabolism in the control of human energy intake (EI) has been well described in adults, remaining however unexplored in adolescents with obesity. The aim of this study was to question the role of body composition, energy expenditure (EE) and substrate metabolism in the control of EI of adolescents with obesity.

methodsAd libitum 24-h EI, body composition (Dual X-ray absorptiometry), Resting Metabolic Rate (RMR, indirect calorimeter) where measured and Total EE obtained during a 36-h stay in metabolic chambers in 26 adolescents (14.1 ± 1.5 years; 14 girls) with severe obesity.

resultsThe mean body weight and Body Mass index were 92.2 ± 17.2 kg and 33.98 ± 4.14 kg.m

conclusionsThe present study provides the first evidence regarding the role of RMR as a main tonic signal of appetite control mediating the effect of body composition and mainly FFM (over FM) on daily EI in adolescents with obesity. It also suggests for the first-time relationships between 24-h CHO and protein oxidation and daily EI in this population.

Indexed as

Body CompositionEnergy IntakeEnergy MetabolismPediatric ObesityAbsorptiometry, PhotonAdolescentBasal MetabolismBody Mass IndexCalorimetry, IndirectFemaleHumansMale

Identifiers

PMID40082598

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.