Evidence map›Paper›PMID 40082563›Full record

ArticleScientific reports2025

Metabolomics insights into the protective molecular mechanism of Vaccinium myrtillus against oxidative stress in intestinal cells.

Sara Novi, Vicky Caponigro, Maria Rosaria Miranda, Giovanna Aquino, Matteo Delli Carri, Emanuela Salviati, Silvia Franceschelli, Carla Sardo, Manuela Giovanna Basilicata, Vincenzo Vestuto and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Anti-Aging Effects ofFoods (Basel, Switzerland) · 2026
    Article
  3. Plant-Based Care and Therapy in Ophthalmology.Antioxidants (Basel, Switzerland) · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Sara Novi *Department of Pharmacy, University of Salerno, Via G. Paolo II, 84084, Fisciano, Salerno, Italy.
Vicky Caponigro *Department of Pharmacy, University of Salerno, Via G. Paolo II, 84084, Fisciano, Salerno, Italy.
Maria Rosaria MirandaDepartment of Pharmacy, University of Salerno, Via G. Paolo II, 84084, Fisciano, Salerno, Italy.
Giovanna AquinoDepartment of Pharmacy, University of Salerno, Via G. Paolo II, 84084, Fisciano, Salerno, Italy.
Matteo Delli CarriDepartment of Pharmacy, University of Salerno, Via G. Paolo II, 84084, Fisciano, Salerno, Italy.
Emanuela SalviatiDepartment of Pharmacy, University of Salerno, Via G. Paolo II, 84084, Fisciano, Salerno, Italy.
Silvia FranceschelliDepartment of Pharmacy, University of Salerno, Via G. Paolo II, 84084, Fisciano, Salerno, Italy.
Carla SardoDepartment of Pharmacy, University of Salerno, Via G. Paolo II, 84084, Fisciano, Salerno, Italy.
Manuela Giovanna BasilicataDepartment of Advanced Medical and Surgical Sciences, University of Campania "Luigi Vanvitelli", Naples, Italy. manuelagiovanna.basilicata@unicampania.it.
Vincenzo VestutoDepartment of Pharmacy, University of Salerno, Via G. Paolo II, 84084, Fisciano, Salerno, Italy. vvestuto@unisa.it.
Mario Felice TecceDepartment of Pharmacy, University of Salerno, Via G. Paolo II, 84084, Fisciano, Salerno, Italy.
Federico MariniDepartment of Chemistry, University of Rome "La Sapienza", Piazzale Aldo Moro 5, 00185, Rome, Italy.
Giacomo PepeDepartment of Pharmacy, University of Salerno, Via G. Paolo II, 84084, Fisciano, Salerno, Italy.
Pietro CampigliaDepartment of Pharmacy, University of Salerno, Via G. Paolo II, 84084, Fisciano, Salerno, Italy.
Michele ManfraDepartment Health Science, University of Basilicata, Viale dell'Ateneo Lucano, 85100, Potenza, Italy.

Funding

Ministero dell'Istruzione, dell'Università e della Ricerca NextGenerationEU. Project code CN_00000033, Concession Decree No. 1034 of 17 June 2022 adopted by the Italian Ministry of University and Research, CUP: D43C22001260001, Project title "National Biodiversity Future Center - NBFC"Ministero dell'Università e della Ricerca Project CN00000041-CENTRO NAZIONALE DI RICERCA "SVILUPPO DI TERAPIA GENICA E FARMACI CON TECNOLOGIA A RNA" Tematica PNRR M4C2-CUP: D43C22001200001
6 · The paper itself

Abstract

Blueberry (Vaccinium myrtillus L.) is a rich source of secondary metabolites known for their potent antioxidant, anti-inflammatory, and cytoprotective properties. These compounds are essential in neutralizing reactive oxygen species (ROS), which are implicated in oxidative stress-related diseases. In this study, we induced oxidative stress in IEC-6 small intestine cells using hydrogen peroxide (H

Indexed as

MetabolomicsOxidative StressPlant ExtractsVaccinium myrtillusAnimalsAntioxidantsApoptosisCell LineHydrogen PeroxideMetabolomeRatsReactive Oxygen SpeciesAntioxidantsHydrogen PeroxidePlant ExtractsReactive Oxygen SpeciesAntioxidantsBlueberryFood scienceHigh-resolution mass spectrometryIn-cell studiesMetabolomics

Identifiers

PMID40082563
PMCPMC11906781

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.