Evidence map›Paper›PMID 40082471›Full record

ArticleNPJ systems biology and applications2025

Enhancing yeast cell tracking with a time-symmetric deep learning approach.

Gergely Szabó, Paolo Bonaiuti, Andrea Ciliberto, András Horváth

Abstract read
In one paragraph

Article in NPJ systems biology and applications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Gergely SzabóITK, PPCU, Práter st. 50/A, Budapest, 1083, Hungary. szabo.gergely@itk.ppke.hu.ORCID http://orcid.org/0009-0002-5700-6051
Paolo BonaiutiIFOM, Via Adamello, 16, Milan, 20139, Italy.ORCID http://orcid.org/0000-0002-4446-9682
Andrea CilibertoITK, PPCU, Práter st. 50/A, Budapest, 1083, Hungary.
András HorváthITK, PPCU, Práter st. 50/A, Budapest, 1083, Hungary. horvath.andras@itk.ppke.hu.ORCID http://orcid.org/0000-0001-5855-4186

Funding

Associazione Italiana per la Ricerca sul Cancro (Italian Association for Cancer Research) AIRC IG-21556Nemzeti Kutatási, Fejlesztési és Innovációs Hivatal (NKFI Office) TKP2021-EGA-42
6 · The paper itself

Abstract

Accurate tracking of live cells using video microscopy recordings remains a challenging task for popular state-of-the-art image processing-based object tracking methods. In recent years, many applications have attempted to integrate deep-learning frameworks for this task, but most still heavily rely on consecutive frame-based tracking or other premises that hinder generalized learning. To address this issue, we aimed to develop a novel deep-learning-based tracking method that assumes cells can be tracked by their spatio-temporal neighborhood, without a restriction to consecutive frames. The proposed method has the additional benefit that the motion patterns of the cells can be learned by the predictor without any prior assumptions, and it has the potential to handle a large number of video frames with heavy artifacts. The efficacy of the proposed method is demonstrated through biologically motivated validation strategies and compared against multiple state-of-the-art cell tracking methods on budding yeast recordings and simulated samples.

Indexed as

Cell TrackingDeep LearningImage Processing, Computer-AssistedSaccharomyces cerevisiaeAlgorithmsMicroscopy, Video

Identifiers

PMID40082471
PMCPMC11906826

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.