Evidence map›Paper›PMID 40082313›Full record

ArticleArchives of gynecology and obstetrics2025

Twin delivery: does induction of labor make a difference?

L Rüegg, L Vonzun, J Wawrla-Zepf, F Krähenmann, N Ochsenbein-Kölble

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Article in Archives of gynecology and obstetrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

L RüeggDepartment of Obstetrics, University Hospital Zurich, Rämistrasse 100, 8091, Zurich, Switzerland. ladina.rueegg@usz.ch.ORCID 0000-0002-4663-9614
L VonzunDepartment of Obstetrics, University Hospital Zurich, Rämistrasse 100, 8091, Zurich, Switzerland.
J Wawrla-ZepfDepartment of Obstetrics, University Hospital Zurich, Rämistrasse 100, 8091, Zurich, Switzerland.
F KrähenmannDepartment of Obstetrics, University Hospital Zurich, Rämistrasse 100, 8091, Zurich, Switzerland.
N Ochsenbein-KölbleDepartment of Obstetrics, University Hospital Zurich, Rämistrasse 100, 8091, Zurich, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeInduction of labor as well as delivery in twin pregnancies bears specific risks. The goal of this study was to analyze the delivery mode in twin pregnancies and influence of induction on the cesarean delivery (CD) rate and perinatal outcome and to identify risk factors for CD and an intertwin interval ≥ 15 min.

methodsThis single-center retrospective cohort study analyzed the outcome of 267 twin pregnancies. Inclusion criteria for vaginal delivery in twins are gestational age (GA) > 34 weeks, leading twin in cephalic presentation, estimated weight difference ≤ 500 g and no previous uterine surgery. Women were divided into three groups: 1 = vaginal delivery, 2 = CD for both twins, 3 = emergency CD for second twin. Outcomes were mode of delivery, and influence of induction on the CD rate.

resultsWe had 156 women (58%) in group 1, 97 (36%) in 2 and 14 (5%) in 3. Induction of labor was performed in 147 cases and led to a higher CD rate (23% vs. 47%, p < 0.001). Induction of labor and nulliparity were associated with a higher risk for CD for both twins. Risk factors for an intertwin interval of ≥ 15 min were maternal age and weight of the second twin. An intertwin interval of ≥ 15 min was associated with a lower umbilical artery pH in the second twin.

conclusionThe rate of CD doubled if induction of labor was necessary. These results emphasize on careful patient counseling that includes information about the risks of deliveries in twin pregnancies.

Indexed as

Cesarean SectionDelivery, ObstetricLabor, InducedPregnancy, TwinAdultFemaleGestational AgeHumansParityPregnancyPregnancy OutcomeRetrospective StudiesRisk FactorsTime FactorsYoung AdultInduction of laborIntertwin intervalMode of deliveryTwin deliveryTwins

Identifiers

PMID40082313
PMCPMC12176924

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.