Evidence map›Paper›PMID 40082179›Full record

ArticleThe journal of prevention of Alzheimer's disease2025

Current status and future directions for the diagnosis and management of mild cognitive impairment in Southeast Asia: A SEACURE consensus paper.

Gursimar Bhalla, Pricilia Tanoto, Ashwati Vipin, Xiao Yuan James Chen, Yi Jin Leow, Christopher Chen, Philip Lin Kiat Yap, Reshma A Merchant, Saima Hilal, Anam Paulus Ong and 11 more

Abstract readConsensus Statement
In one paragraph

Article in The journal of prevention of Alzheimer's disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Gursimar BhallaDementia Research Centre (Singapore), Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore.
Pricilia TanotoDementia Research Centre (Singapore), Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore.
Ashwati VipinDementia Research Centre (Singapore), Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore.
Xiao Yuan James ChenDementia Research Centre (Singapore), Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore.
Yi Jin LeowDementia Research Centre (Singapore), Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore.
Christopher ChenMemory Aging and Cognition Centre, Department of P2Memory Aging and Cognition Centre, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Philip Lin Kiat YapDepartment of Geriatric Medicine, Khoo Teck Puat Hospital, Singapore.
Reshma A MerchantDivision of Geriatric Medicine, Department of Medicine, National University Hospital, Singapore, Singapore.
Saima HilalNUS Saw Swee Hock School of Public Health, Singapore; Department of Pharmacology, National University of Singapore, Singapore; Memory Aging and Cognition Center, National University Health System, Singapore; Department of Epidemiology and Radiology and Nuclear Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands.
Anam Paulus OngDepartment of Neurology, Faculty of Medicine, Padjadjaran University, Bandung, Indonesia.
Encarnita Raya AmpilDepartment of Neuroscience and Behavioral Medicine, University of Santo Tomas Hospital, Manila, Philippines; Memory Center, Institute for Neurosciences, St. Luke's Medical Center Global City, Manila, Philippines.
Mohamad Imran IdrisDepartment of Medicine, Faculty of Medicine, University of Malaya, Malaysia.
Irene LooiClinical Research Center, Seberang Jaya Hospital, Penang, Malaysia; Medical Department, Seberang Jaya Hospital, Penang, Malaysia.
Jacqueline DominguezInstitute for Neurosciences, St. Luke's Medical Center, Quezon, Philippines.
Suraya YusoffNewcastle University Medicine Malaysia (NUMed), Malaysia; Malaysian Psychiatric Association (MPA), Malaysia; Malaysian Society of Neurosciences (MSN), Malaysia.
Maw Pin TanAgeing and Age-Associated Disorders Research Group, Department of Medicine, Faculty Medicine, Universiti Malaya, Kuala Lumpur, Malaysia.
Cong Thang TranUniversity of Medicine and Pharmacy at Ho Chi Minh City, Vietnam.
Mai Trang TongDepartment of Neurology, University Medical Center Ho Chi Minh City, Vietnam.
Vorapun SenanarongDepartment of Medicine, Division of Neurology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Yuda TuranaAtma Jaya Catholic University of Indonesia, Department of Neurology, Faculty of Medicine, Indonesia.
Nagaendran KandiahDementia Research Centre (Singapore), Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore; Neuroscience and Mental Health Programme, Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore; National Healthcare Group, Singapore. Electronic address: nagaendran_kandiah@ntu.edu.sg.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Global aging populations are facing increased prevalence of mild cognitive impairment (MCI) - the preclinical stage of dementia characterized by single/multi-domain neurocognitive decline that does not impair an individual's normal daily functioning. Asian populations are at increased risk of developing MCI and dementia, and many cases go undetected in Southeast Asia (SEA), resulting in increased burden on patients, caregivers and national healthcare systems. There is an urgent need for efficient and scalable diagnostic and management strategies across SEA. Our findings illustrate that current strategies are limited by insufficient resources and a lack of awareness, particularly in developing SEA nations. Strategies for improving the MCI landscape in SEA include increasing widespread community awareness and cognitive health screenings for individuals with a history of vascular risk factors, validation of traditional cognitive screening tests in the respective countries, greater access to blood-biomarker testing, and the development and validation of novel digitized diagnostics.

Indexed as

Cognitive DysfunctionAsia, SoutheasternBiomarkersHumansNeuropsychological TestsBiomarkersEarly diagnosisMild cognitive impairmentSoutheast Asia

Identifiers

PMID40082179
PMCPMC12183928

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.