Evidence map›Paper›PMID 40082002›Full record

ArticleBMJ open2025

Approaches for thoracoabdominal oesophagectomy for oesophageal cancer: a network meta-analysis - study protocol.

Artur Rebelo, Juliane Friedrichs, Maurizio Grilli, Johannes Vey, Johannes Klose, Marie Merling, Joerg Kleeff, Ulrich Ronellenfitsch

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMJ open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Artur RebeloDepartment of Visceral, Vascular and Endocrine Surgery, Martin Luther University of Halle Wittenberg Faculty of Medicine, Halle (Saale), Germany artur.rebelo@uk-halle.de.ORCID http://orcid.org/0000-0002-5267-079X
Juliane FriedrichsDepartment of Visceral, Vascular and Endocrine Surgery, Martin Luther University of Halle Wittenberg Faculty of Medicine, Halle (Saale), Germany.ORCID http://orcid.org/0000-0001-8653-3948
Maurizio GrilliLibrary of the Medical Faculty, Mannheim, Heidelberg University, Mannheim, Germany, UK.
Johannes VeyUniversity Hospital Heidelberg, Germany, Institute of Medical Biometry, Heidelberg, Germany, Heidelgerg, Germany.
Johannes KloseDepartment of Visceral, Vascular and Endocrine Surgery, Martin Luther University of Halle Wittenberg Faculty of Medicine, Halle (Saale), Germany.
Marie MerlingUniversity Hospital Heidelberg, Germany, Institute of Medical Biometry, Heidelberg, Germany, Heidelgerg, Germany.
Joerg KleeffDepartment of Visceral, Vascular and Endocrine Surgery, Martin Luther University of Halle Wittenberg Faculty of Medicine, Halle (Saale), Germany.
Ulrich RonellenfitschDepartment of Visceral, Vascular and Endocrine Surgery, Martin Luther University of Halle Wittenberg Faculty of Medicine, Halle (Saale), Germany.ORCID http://orcid.org/0000-0003-1107-813X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionOesophageal cancer is the seventh most frequently diagnosed cancer and the sixth leading cause of cancer-related deaths worldwide. Oesophagectomy remains the main curative treatment option. The effect of different surgical approaches (completely open, hybrid, completely minimally invasive and robot-assisted) on patients undergoing thoracoabdominal oesophagectomy (Ivor-Lewis's procedure) for oesophageal cancer is evaluated, focusing on overall survival, postoperative mortality and morbidity. METHODS AND ANALYSIS: A systematic literature search will be conducted in PubMed/Medline, Cochrane Library, Embase, Cumulated Index in Nursing and Allied Health Literature, ClinicalTrials.gov and International Clinical Trials Registry Platform using predefined search terms. A random-effects (network) meta-analysis using the frequentist framework will be performed. ETHICS AND DISSEMINATION: As this study is based on previously published data, no ethical approval is required. Findings will be disseminated through peer-reviewed publications and conference presentations to inform clinical decision-makers (eg, surgeons, gastroenterologists). TRAIL REGISTRATION NUMBER: CRD42024564915.

Indexed as

Esophageal NeoplasmsEsophagectomyHumansNetwork Meta-Analysis as TopicPostoperative ComplicationsResearch DesignRobotic Surgical ProceduresSystematic Reviews as TopicMeta-AnalysisNetwork Meta-AnalysisOesophageal diseaseRandomised Controlled TrialSURGERY

Identifiers

PMID40082002
PMCPMC11907055

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.