Evidence map›Paper›PMID 40081998›Full record

ArticleBMJ open2025

Improving Outcomes in Mental Health (IOMH)-an Australian longitudinal clinical study of families with children with neurodevelopmental problems: cohort profile.

Dana E Galligan, Leanne Payne, Daniel P Sullivan, Madhura Bhadravathi Lokeshappa, Laura Ziser, Lorelle Nunn, Leanne M Wallace, Isabella Andersen, Sophie Howarth, Akina Kato and 12 more

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Article in BMJ open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Dana E GalliganChild Health Research Centre, The University of Queensland, Brisbane, Queensland, Australia.ORCID http://orcid.org/0000-0003-0045-3045
Leanne PayneChild Health Research Centre, The University of Queensland, Brisbane, Queensland, Australia.
Daniel P SullivanChild Health Research Centre, The University of Queensland, Brisbane, Queensland, Australia.ORCID http://orcid.org/0000-0002-1782-1935
Madhura Bhadravathi LokeshappaInstitute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland, Australia.
Laura ZiserInstitute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland, Australia.
Lorelle NunnInstitute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland, Australia.
Leanne M WallaceInstitute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland, Australia.
Isabella AndersenChild Health Research Centre, The University of Queensland, Brisbane, Queensland, Australia.
Sophie HowarthChild Health Research Centre, The University of Queensland, Brisbane, Queensland, Australia.
Akina KatoChild Health Research Centre, The University of Queensland, Brisbane, Queensland, Australia.
Mohan KarunanithiChild Health Research Centre, The University of Queensland, Brisbane, Queensland, Australia.ORCID http://orcid.org/0000-0002-9141-932X
Cassandra MinginChild Health Research Centre, The University of Queensland, Brisbane, Queensland, Australia.
Sally O'ScanaillChild Health Research Centre, The University of Queensland, Brisbane, Queensland, Australia.
Nisreen AouiraChild Health Research Centre, The University of Queensland, Brisbane, Queensland, Australia.
Ayu ParamecwariChild Health Research Centre, The University of Queensland, Brisbane, Queensland, Australia.
Matthew R SandersThe University of Queensland Parenting and Family Support Centre, Brisbane, Queensland, Australia.
Vanessa E CobhamSchool of Psychology, The University of Queensland, Brisbane, Queensland, Australia.
Naomi R WrayInstitute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland, Australia.
Anjali K HendersInstitute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland, Australia.
Enda M ByrneChild Health Research Centre, The University of Queensland, Brisbane, Queensland, Australia.ORCID http://orcid.org/0000-0002-9491-7797
Honey Heussler *Child Health Research Centre, The University of Queensland, Brisbane, Queensland, Australia.
Christel M Middeldorp *Child Health Research Centre, The University of Queensland, Brisbane, Queensland, Australia c.middeldorp@uq.edu.au.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeChildren with neurodevelopmental disorders (NDDs) such as autism spectrum disorder (ASD) and attention-deficit hyperactivity disorder (ADHD) face a range of challenges which impact their daily functioning and that of their family. NDDs are often associated with significant mental health problems which can influence the course. The Improving Outcomes in Mental Health cohort described in this article aims to investigate the risk factors for the persistence and severity of mental health problems in children with NDDs.

participantsA total of 1084 families (primary caregivers and children) were recruited from the Child Development Program at the Children's Health Queensland Hospital and Health Service in Brisbane, Australia. 1471 caregivers (female n=1036) participated in the study, which included 382 families with 2 or more caregivers participating. The children were predominantly male (71%), with the average age of all children 5.6 years. FINDINGS TO DATE: The most prevalent child clinical diagnoses were ASD and ADHD, with half of children receiving more than one diagnosis. Caregiver reports indicated that children were experiencing clinical levels of depression (30.8%) and anxiety (27.6%). Approximately 39% of caregivers scored in the subclinical or clinical range for at least one Diagnostic and Statistical Manual of Mental Disorders measure, the majority reporting depressive problems. FUTURE PLANS: Future plans for this data set include analysis of environmental variables such as family structure, income, school achievements and leisure activities as risk factors for the persistence of mental health problems in children with NDDs. Genetic data will be used to provide insights into the heritability of mental illness and improve prediction.

Indexed as

Attention Deficit Disorder with HyperactivityAutism Spectrum DisorderCaregiversMental HealthNeurodevelopmental DisordersAdolescentAdultAnxietyAustraliaChildChild, PreschoolDepressionFemaleHumansLongitudinal StudiesMaleAnxiety disordersChild & adolescent psychiatryDepression & mood disorders

Identifiers

PMID40081998
PMCPMC11906980

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.