Evidence map›Paper›PMID 40081910›Full record

ArticleSexually transmitted infections2025

Characterisation of a syndemic of STI symptoms, substance use and violence among incarcerated Peruvian women.

Elena Cyrus, Rodman Turpin, Typhanye Dyer, Elika Hashemi, Sobur Ali, Andrea Cornejo Bazo, Antonio Morgan-Lopez, Joy D Scheidell, Segundo R Leon, Michael Sciaudone and 1 more

Abstract read
In one paragraph

Article in Sexually transmitted infections, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Elena CyrusDepartment of Population Health Sciences, University of Central Florida, Orlando, Florida, USA Elena.Cyrus@ucf.edu.
Rodman TurpinDepartment of Global and Community Health, George Mason University, Fairfax, Virginia, USA.
Typhanye DyerEpidemiology and Biostatistics, University of Maryland School of Public Health, College Park, Maryland, USA.
Elika HashemiDepartment of Population Health Sciences, University of Central Florida, Orlando, Florida, USA.
Sobur AliDepartment of Population Health Sciences, University of Central Florida, Orlando, Florida, USA.ORCID http://orcid.org/0000-0002-0376-8803
Andrea Cornejo BazoInternational Degrees Department, Universidad Peruana de Ciencias Aplicadas, Lima, Peru.
Antonio Morgan-LopezRTI International, Research Triangle Park, Carolina, USA.
Joy D ScheidellUniversity of Central Florida, Orlando, Florida, USA.ORCID http://orcid.org/0000-0001-5504-149X
Segundo R LeonUniversidad Privada San Juan Bautista, Lima, Peru.ORCID http://orcid.org/0000-0002-5630-5714
Michael SciaudoneTulane University, New Orleans, Louisiana, USA.
Frederick L AlticeDepartment of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, Connecticut, USA.

Funding

Research Mentoring and Building Capacity of underrepresented Minority Research Scientists in India.D43TW010540 · FIC · YALE UNIVERSITY · PI MICHELE BARRY, Eva Harris · 2017 to 2026
$15.5M
ENTRUST - economic navigation and strengthening to realize unrestricted services for transgender womenDP2DA058436 · NIDA · UNIVERSITY OF CENTRAL FLORIDA · PI CYRUS, ELENA · 2023 to 2023
$2.3M
Malaysian Implementation Science Training (MIST) Program in HIVD43TW011324 · FIC · YALE UNIVERSITY · PI FREDERICK LEWIS ALTICE, Rafdzah Zaki · 2020 to 2026
$1.8M
To Reach Unrestricted Services for Transgender Women (TRUST)R00DA046311 · NIDA · UNIVERSITY OF CENTRAL FLORIDA · PI CYRUS, ELENA · 2020 to 2022
$747k
To Reach Unrestricted Services for Transgender Women (TRUST)K99DA046311 · NIDA · FLORIDA INTERNATIONAL UNIVERSITY · PI CYRUS, ELENA · 2018 to 2019
$339k
FIC NIH HHS D43 TW010540FIC NIH HHS D43 TW011324NIAAA NIH HHS L30 AA027051NIDA NIH HHS DP2 DA058436NIDA NIH HHS K99 DA046311NIDA NIH HHS R00 DA046311
6 · The paper itself

Abstract

objectivesDespite parallel global trends of increasing incarceration rates and sexually transmitted infections (STIs) among women, STI epidemiological data for this vulnerable at-risk population are limited. The study objective was to characterise patterns of STI symptoms and explore covariates and drivers of indicating STI symptoms using syndemic theory among a population of incarcerated women in Peru.

methodsIn a cross-sectional study, a sample of 249 incarcerated women responded to a questionnaire on substance use, depression, sexual behaviour, STI symptoms and violence, among other variables, between May and July 2015 in Santa Manica Prison (Lima, Peru). Univariate and bivariate analyses informed a latent profile analysis (LPA) and logistic regression.

resultsMost women (93.5%) were Peruvian; 86.6% had prison sentences <5 years; the median age was 37 years (range 18-70 years); 2.6% were pregnant, 7.2% had children residing with them in prison; most women (78.7%) had a high school degree; >1/3 of the sample had ≥2 STI symptoms. The LPA analysis revealed that 39% of the sample had a 'syndemic' profile (co-occurrence of multiple STI symptoms, experiences of violence and substance use). Approximately 87% of women who were characterised by the syndemic profile were <50 years of age. The 'syndemic' profile was associated with double the prevalence of having multiple STI symptoms (≥2 symptoms: Prevalence Ratio (PR)=1.88 (95% CI 1.18, 2.99); ≥3 symptoms: PR=2.55 (95% CI 1.32, 4.93)).

conclusionsTo address this syndemic, younger incarcerated women presenting with co-occurring STI symptoms (>2) can be clinically screened for diagnosis and treatment and assessed for substance use and risk of violence. Further research in this area may help stem and prevent deleterious health outcomes, including STIs, abuse and substance misuse, that can impact the individual and families.

Indexed as

PrisonersSexually Transmitted DiseasesSubstance-Related DisordersSyndemicViolenceAdolescentAdultAgedCross-Sectional StudiesFemaleHumansMiddle AgedPeruPrevalenceRisk FactorsSexual BehaviorINFECTIONPRISONERSWOMEN

Identifiers

PMID40081910
PMCPMC12573386

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.