ArticleClinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery2025
Comparison of ChatGPT-4, Copilot, Bard and Gemini Ultra on an Otolaryngology Question Bank.
Article in Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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4 citing papers in PubMed.
- Performance of Seven Large Language Models on Anatomy Examination Questions.Clinical anatomy (New York, N.Y.) · 2026Article
- Comparative performance of artificial intelligence models in intensive care nursing questions: an evaluation of ChatGPT, DeepSeek, and Google Gemini.BMC nursing · 2026Article
- Comparison of ChatGPT and DeepSeek on a Standardized Audiologist Qualification Examination in Chinese: Observational Study.JMIR formative research · 2025Observational
- The Application and Diagnostic Accuracy of Artificial Intelligence in Rhinology: A Review.Cureus · 2025Review
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8 authors.
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Abstract
objectiveTo compare the performance of Google Bard, Microsoft Copilot, GPT-4 with vision (GPT-4) and Gemini Ultra on the OTO Chautauqua, a student-created, faculty-reviewed otolaryngology question bank. STUDY
designComparative performance evaluation of different LLMs.
settingN/A.
participantsN/A.
methodsLarge language models (LLMs) are being extensively tested in medical education. However, their accuracy and effectiveness remain understudied, particularly in otolaryngology. This study involved inputting 350 single-best-answer multiple choice questions, including 18 image-based questions, into four LLMS. Questions were sourced from six independent question banks related to (a) rhinology, (b) head and neck oncology, (c) endocrinology, (d) general otolaryngology, (e) paediatrics, (f) otology, (g) facial plastics, reconstruction and (h) trauma. LLMs were instructed to provide an output reasoning for their answers, the length of which was recorded.
resultsAggregate and subgroup analysis revealed that Gemini (79.8%) outperformed the other LLMs, followed by GPT-4 (71.1%), Copilot (68.0%), and Bard (65.1%) in accuracy. The LLMs had significantly different average response lengths, with Bard (x̄ = 1685.24) being the longest and no difference between GPT-4 (x̄ = 827.34) and Copilot (x̄ = 904.12). Gemini's longer responses (x̄ =1291.68) included explanatory images and links. Gemini and GPT-4 correctly answered image-based questions (n = 18), unlike Copilot and Bard, highlighting their adaptability and multimodal capabilities.
conclusionGemini outperformed the other LLMs in terms of accuracy, followed by GPT-4, Copilot and Bard. GPT-4, although it has the second-highest accuracy, provides concise and relevant explanations. Despite the promising performance of LLMs, medical learners should cautiously assess accuracy and decision-making reliability.
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