Evidence map›Paper›PMID 40081656›Full record

ArticleChest2025

Phenotyping Exertional Breathlessness Using Cardiopulmonary Cycle Exercise Testing in People With Chronic Airflow Limitation.

Magnus Ekström, Pei Zhi Li, Hayley Lewthwaite, Jean Bourbeau, Wan C Tan, Dennis Jensen, Canadian Cohort Obstructive Lung Disease Collaborative Research Group

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chest, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Magnus EkströmDepartment of Clinical Sciences Lund, Respiratory Medicine, Allergology and Palliative Medicine, Faculty of Medicine, Lund University, Lund, Sweden. Electronic address: magnus.ekstrom@med.lu.se.
Pei Zhi LiMontreal Chest Institute, Montréal, QC, Canada.
Hayley LewthwaiteClinical Exercise and Respiratory Physiology Laboratory, Department of Kinesiology and Physical Education, Faculty of Education, McGill University, Montréal, QC, Canada; Centre of Research Excellence in Treatable Traits, College of Health, Medicine and Wellbeing, University of Newcastle, NSW, Australia; Asthma and Breathing Research Program, Hunter Medical Research Institute, New Lambton, NSW, Australia.
Jean BourbeauMontreal Chest Institute, Montréal, QC, Canada; Translational Research in Respiratory Diseases Program and Respiratory Epidemiology and Clinical Research Unit, McGill University Health Centre Research Institute, Montréal, QC, Canada.
Wan C TanCentre for Heart Lung Innovation, Department of Medicine, University of British Columbia, Vancouver, BC, Canada.
Dennis JensenTranslational Research in Respiratory Diseases Program and Respiratory Epidemiology and Clinical Research Unit, McGill University Health Centre Research Institute, Montréal, QC, Canada.
Canadian Cohort Obstructive Lung Disease Collaborative Research Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundExertional breathlessness is a cardinal symptom of people with chronic airflow limitation (CAL) and can be evaluated using cardiopulmonary exercise testing (CPET). RESEARCH QUESTION: Does abnormally high exertional breathlessness in relationship to the rate of oxygen uptake (V'O STUDY DESIGN AND

methodsAnalysis of people aged ≥ 40 years with CAL (FEV

resultsWe included 325 people (44% female) with CAL (mean [SD]) FEV

interpretationOur results show that exertional breathlessness phenotyped in relationship to V'O

Indexed as

DyspneaExercise TestPulmonary Disease, Chronic ObstructiveAdultAgedCanadaExercise ToleranceFemaleForced Expiratory VolumeHumansMaleMiddle AgedOxygen ConsumptionPhenotypedyspneaexercise capacitymechanismsoutcomesventilation

Identifiers

PMID40081656
PMCPMC12405935

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.