Evidence map›Paper›PMID 40080898›Full record

ReviewTechnology in cancer research & treatment

Circular RNAs as Biomarkers in Breast Cancer Diagnosis, Prognosis, Molecular Types, Metastasis and Drug Resistance.

Li-Xin Li, Yun Hao, Lei Dong, Zhong-Qi Qiao, Shun-Chao Yang, Yan-Duo Chen, Kai Zhang, Ya-Wen Wang

Abstract readReview
In one paragraph

Review in Technology in cancer research & treatment. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Subtype-Specific mInternational journal of molecular sciences · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Li-Xin LiDepartment of Breast Surgery, General Surgery, Qilu Hospital of Shandong University, Jinan, Shandong, People's Republic of China.
Yun HaoDepartment of Breast Surgery, General Surgery, Qilu Hospital of Shandong University, Jinan, Shandong, People's Republic of China.ORCID 0009-0003-2577-6614
Lei DongDepartment of Breast Surgery, General Surgery, Qilu Hospital of Shandong University, Jinan, Shandong, People's Republic of China.
Zhong-Qi QiaoDepartment of Breast Surgery, General Surgery, Qilu Hospital of Shandong University, Jinan, Shandong, People's Republic of China.
Shun-Chao YangDepartment of Breast Surgery, General Surgery, Qilu Hospital of Shandong University, Jinan, Shandong, People's Republic of China.
Yan-Duo ChenDepartment of Pediatric Surgery, Central Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, People's Republic of China.
Kai ZhangDepartment of Breast Surgery, General Surgery, Qilu Hospital of Shandong University, Jinan, Shandong, People's Republic of China.
Ya-Wen WangDepartment of Breast Surgery, General Surgery, Qilu Hospital of Shandong University, Jinan, Shandong, People's Republic of China.ORCID 0000-0002-9532-0052

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Breast cancer is one of the leading causes of cancer-related deaths in women worldwide. Circular RNAs (circRNAs), a novel class of endogenous noncoding RNA with a covalently closed continuous loop that lacks the 5'-cap structure and the 3'-poly A tail, are more stable than linear RNAs and less susceptible to degradation by nucleases. CircRNAs are widespread in multiple mammalian genomes and have been detected in various tissues, cells and body fluids. Increasing evidence shows that abnormal expression of circRNAs is involved in the development of a variety of diseases, including breast cancer. Numerous studies have explored the potential of circRNAs as biomarkers in various malignant tumors. In this review, we aim to provide a comprehensive overview of the latest advances in circRNAs as promising biomarkers in the early diagnosis, prognosis, molecular type, metastasis and drug resistance of breast cancer.

Indexed as

Biomarkers, TumorBreast NeoplasmsDrug Resistance, NeoplasmRNA, CircularFemaleGene Expression Regulation, NeoplasticHumansNeoplasm MetastasisPrognosisBiomarkers, TumorRNA, Circularbiomarkerbreast cancercircRNAsdiagnosisdrug resistancemetastasismolecular typeprognosis

Identifiers

PMID40080898
PMCPMC11907621

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.