Evidence map›Paper›PMID 40080805›Full record

Trial reportThe Journal of urology2025

Comparison of Complication and Readmission Rates Between Robot-Assisted and Open Radical Cystectomy: Results From the Randomized RAZOR Clinical Trial.

Vivek Venkatramani, Isildinha M Reis, Mark L Gonzalgo, Sanjaya Swain, Robert S Svatek, Dipen J Parekh

Registry-linked trialAbstract readClinical Trial, Phase IIIComparative StudyEquivalence Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in The Journal of urology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01157676 (Open Vs Robotic-Assisted Radical Cystectomy), which is not on this map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01157676 nacompletednot on this map

Open Vs Robotic-Assisted Radical Cystectomy: A Randomized Trial

TypeinterventionalSponsorUniversity of MiamiRan2011 to 2018Enrolled350ConditionsBladder Cancer Requiring CystectomyArmsOpen radical cystectomy, Robotic assisted radical cystectomy, DaVinci robot
3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Vivek VenkatramaniDepartment of Urology, University of Miami Miller School of Medicine, Miami, Florida.ORCID 0000-0001-6821-7132
Isildinha M ReisSylvester Comprehensive Cancer Center, University of Miami, Miami, Florida.ORCID 0000-0002-7695-8771
Mark L GonzalgoDepartment of Urology, University of Miami Miller School of Medicine, Miami, Florida.ORCID 0000-0003-0476-0288
Sanjaya SwainDepartment of Urology, University of Miami Miller School of Medicine, Miami, Florida.
Robert S SvatekDivision of Urologic Oncology, Department of Urology, University of Texas Health Science Center at San Antonio, San Antonio, Texas.ORCID 0000-0002-0239-1338
Dipen J ParekhDepartment of Urology, University of Miami Miller School of Medicine, Miami, Florida.ORCID 0000-0002-8261-5185

Funding

Open vs Robot-Assisted Radical Cystectomy: A Randomized TrialR01CA155388 · NCI · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI PAREKH, DIPEN · 2011 to 2015
$3.1M
NCI NIH HHS R01 CA155388
6 · The paper itself

Abstract

purposeWe assessed differences in complications and readmissions between robot-assisted radical cystectomy (RARC) and open radical cystectomy (ORC). MATERIALS AND

methodsThis study uses data from the per-protocol population of the Randomized Robotic-Assisted vs Open Radical Cystectomy (RAZOR) study, a multicenter, open-label, phase 3, noninferiority clinical trial. RAZOR enrolled across 15 academic medical centers in the United States between 2011 and 2014. The median follow-up was 2 years. Complications up to 90 days using the Clavien-Dindo classification, and readmissions at 90 days and 1 year postoperatively were compared. Multivariable logistic regression analyses were performed to determine any predictors of major complications and of postsurgery readmission.

resultsBaseline characteristics were similar, and there was no significant difference in overall and major complication rates between RARC (n = 150) and ORC (n = 152) arms. Simplified frailty index ≥ 3 (HR, 4.22, 95% CI, 2.67-6.66,

conclusionsNo significant differences in major complications and readmission rates between ORC and RARC were noted. Patient frailty was an important predictor of these outcomes, and special attention needs to be taken in ensuring appropriate patient selection and preoperative preparation.

trial registrationClinicalTrials.gov Identifier: NCT01157676.

Indexed as

CystectomyPatient ReadmissionPostoperative ComplicationsRobotic Surgical ProceduresUrinary Bladder NeoplasmsAgedFemaleFollow-Up StudiesHumansMaleMiddle AgedUnited Statesrandomized trialrobotic surgeryurinary bladder cancer

Identifiers

PMID40080805
PMCPMC12064358

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.