Evidence map›Paper›PMID 40080506›Full record

ArticlePloS one2025

Examining perinatal health inequities: The role of disability and risk of adverse outcomes through the U.S. Pregnancy Risk Assessment Monitoring System.

Jeanne L Alhusen, Genevieve R Lyons, Rosemary B Hughes, Kathryn Laughon, Maria McDonald, Casey L Johnson

Abstract read
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Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

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0cells of the map it votes in
4citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Jeanne L AlhusenSchool of Nursing, University of Virginia, Charlottesville, Virginia, United States of America.
Genevieve R LyonsDepartment of Public Health Sciences, School of Medicine, University of Virginia, Charlottesville, Virginia, United States of America.
Rosemary B HughesRural Institute for Inclusive Communities, University of Montana, Missoula, Montana, United States of America.
Kathryn LaughonSchool of Nursing, University of Virginia, Charlottesville, Virginia, United States of America.
Maria McDonaldSchool of Nursing, University of Virginia, Charlottesville, Virginia, United States of America.
Casey L JohnsonSchool of Nursing, University of Virginia, Charlottesville, Virginia, United States of America.ORCID https://orcid.org/0009-0007-8972-8610

Funding

Psychosocial stress and its relation to maternal and infant outcomes among women with disabilitiesR01HD102927 · NICHD · UNIVERSITY OF VIRGINIA · PI ALHUSEN, JEANNE L · 2021 to 2025
$2.3M
NICHD NIH HHS R01 HD102927
6 · The paper itself

Abstract

objectiveTo examine pre-pregnancy characteristics, pregnancy complications, and birth outcomes among respondents with self-reported disability compared to those without disability.

methodsA cross-sectional weighted sample of 2,006,700 respondents with singleton live births who participated in the United States Pregnancy Risk Assessment Monitoring System (PRAMS) between 2018 and 2021 provided data on disability, including difficulty in vision, hearing, ambulation, cognition, communication, and self-care. We estimated covariate-adjusted odds of differences in pre-pregnancy chronic health conditions, pregnancy intention, intimate partner violence (IPV), depression, adequacy of prenatal care, pregnancy-related health conditions, and birth outcomes by disability status.

resultsOf the 2,006,700 respondents included, 59.5% reported no disability, 33.9% had moderate disability, and 6.6% had severe disability. Across most outcomes, there was a graded pattern with those with severe disability having the worst outcomes compared to the other two groups. Respondents with severe disability were more likely to report diabetes and hypertension before becoming pregnant than respondents without disabilities. Those respondents with severe disability or moderate disability had an increased odds of reporting IPV and depression than those with no disability. During pregnancy, respondents with severe disability had an increased odds of gestational diabetes (aOR 1.46, 95% CI 1.18, 1.80) and hypertensive disorders of pregnancy (aOR 1.70, 95% CI 1.43, 2.02) as compared to respondents with no disability. Respondents with moderate disability also had an increased odds of both gestational diabetes (aOR 1.19, 95% CI 1.06, 1.34) and hypertensive disorders of pregnancy (aOR 1.29, 95% CI 1.17, 1.42) as compared to those with no disability. The odds of reporting an unintended pregnancy were highest in respondents with a severe disability (aOR 1.66, 95% CI 1.43, 1.94) and were also increased in respondents with moderate disability (aOR 1.48, 95% CI 1.36, 1.62) as compared to those reporting no disability. Across most birth outcomes, respondents with severe disabilities had worse outcomes with an increased odds of low birth weight infants (aOR 1.28, 95% CI 1.08, 1.52), preterm birth (aOR 1.32, 95% CI 1.11, 1.57), and neonatal intensive care unit admission (aOR 1.45, 95% CI 1.02, 2.06) as compared to respondents with no disability. There were not differences in being classified as small for gestational age or infants' length of hospital stay by disability status.

conclusionsAcross the perinatal period, respondents with moderate or severe disability experienced worse outcomes than those without disability. There is a critical need to improve pre-conception health in an effort to reduce inequities in pregnancy outcomes. Additionally, health care providers and systems must provide equitable access to care to persons with disabilities to reduce inequities in outcomes.

Indexed as

Health Status DisparitiesPersons with DisabilitiesPregnancy ComplicationsPregnancy OutcomeAdolescentAdultCross-Sectional StudiesFemaleHumansInfant, NewbornPregnancyPrenatal CareRisk AssessmentUnited StatesYoung Adult

Identifiers

PMID40080506
PMCPMC11906042

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.