Evidence map›Paper›PMID 40080408›Full record

ArticleeLife2025

Impaired fatty acid import or catabolism in macrophages restricts intracellular growth of

Nelson V Simwela, Eleni Jaecklein, Christopher M Sassetti, David G Russell

Abstract read
In one paragraph

Article in eLife, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. CRISPRi-mediated silencing of the ABC transporterFrontiers in microbiology · 2026
    Article
  6. Review
  7. Review
  8. Macrophages: sentinels, warriors, and healers.Human molecular genetics · 2025
    Review
  9. Article
  10. Article
  11. Article
  12. Identification ofMicrobiology spectrum · 2025
    Article
  13. Article
  14. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Nelson V SimwelaDepartment of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, United States.ORCID https://orcid.org/0000-0002-4734-0518
Eleni JaeckleinDepartment of Microbiology, UMass Chan Medical School, Worcester, United States.
Christopher M SassettiDepartment of Microbiology, UMass Chan Medical School, Worcester, United States.ORCID https://orcid.org/0000-0001-6178-4329
David G RussellDepartment of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, United States.ORCID https://orcid.org/0000-0002-9748-750X

Funding

Lung immune function in human TB infection and its perturbation by HIV-1.R01AI155319 · NIAID · CORNELL UNIVERSITY · PI MWANDUMBA, HENRY CHARLES, RUSSELL, DAVID G · 2020 to 2024
$3.3M
National Institute of Allergy and Infectious Diseases AI155319National Institute of Allergy and Infectious Diseases AI162598National Institute of Allergy and Infectious Diseases T32AI007349NIAID NIH HHS R01 AI155319NIH Office of the Director OD032135
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Fatty AcidsMacrophagesMycobacterium tuberculosisTuberculosisAnimalsAutophagyCRISPR-Cas SystemsHumansLipid MetabolismMiceFatty Acidsinfectious diseaselipid metabolismmacrophagemicrobiologymousemycobacteriumtuberculosis

Identifiers

PMID40080408
PMCPMC11906158

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.