Evidence map›Paper›PMID 40080237›Full record

ArticleJournal of ophthalmic inflammation and infection2025

Recurrent uveitic macular edema managed with intravitreal faricimab injection.

Negin Yavari, Dalia El Feky, Frances A Anover, Khiem Nguyen, Azadeh Mobasserian, Quan Dong Nguyen, Christopher Or

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In one paragraph

Article in Journal of ophthalmic inflammation and infection, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Negin YavariSpencer Center for Vision Research, Byers Eye Institute at Stanford University, 2452 Watson Court, Suite 200, 94303, Palo Alto, CA, USA.
Dalia El FekySpencer Center for Vision Research, Byers Eye Institute at Stanford University, 2452 Watson Court, Suite 200, 94303, Palo Alto, CA, USA.
Frances A AnoverSpencer Center for Vision Research, Byers Eye Institute at Stanford University, 2452 Watson Court, Suite 200, 94303, Palo Alto, CA, USA.
Khiem NguyenSpencer Center for Vision Research, Byers Eye Institute at Stanford University, 2452 Watson Court, Suite 200, 94303, Palo Alto, CA, USA.
Azadeh MobasserianSpencer Center for Vision Research, Byers Eye Institute at Stanford University, 2452 Watson Court, Suite 200, 94303, Palo Alto, CA, USA.
Quan Dong NguyenSpencer Center for Vision Research, Byers Eye Institute at Stanford University, 2452 Watson Court, Suite 200, 94303, Palo Alto, CA, USA.
Christopher OrSpencer Center for Vision Research, Byers Eye Institute at Stanford University, 2452 Watson Court, Suite 200, 94303, Palo Alto, CA, USA. chrisor@stanford.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo present a case of recurrent uveitic macular edema (UME) treated with intravitreal faricimab injection.

methodsSingle case report from a tertiary referral center. OBSERVATIONS: A 63-year-old Caucasian female presenting with recurrent UME due to birdshot chorioretinopathy (BSCR) in both eyes. UME had been treated with multiple agents including intravenous methylprednisone, posterior subtenons and intravitreal triamcinolone acetonide injection, dexamethasone implant, mycophenolate mofetil, and adalimumab with limited improvement and development of intolerance. Moreover, optical coherence tomography also revealed recurrence of UME with subretinal fluid in both eyes. After treatment with one dose of intravitreal faricimab injection, complete resolution of UME was achieved and maintained for three months.

conclusionThe findings of this case hint towards the potential simultaneous effect of angiopoietin-2 blockade along with vascular endothelia growth factor A inhibition by faricimab in managing treatment-resistant UME. Nonetheless, more studies focusing on the role of intravitreal faricimab in UME are required.

Indexed as

Birdshot chorioretinopathyIntravitreal anti-vascular endothelial growth factorIntravitreal faricimab injectionRetinal vasculitisUveitic macular edema

Identifiers

PMID40080237
PMCPMC11906930

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.