ReviewGraefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie2025
Premacular membranes and glaucoma: a review of clinical and therapeutic considerations.
Review in Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Impact of glaucoma on outcomes after epiretinal membrane surgery. a pairwise and post-hoc single-arm meta-analysis.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposePrimary epiretinal, or more precisely termed pre macular membranes (PMM) and glaucomatous optic neuropathy are both common conditions affecting a predominantly elderly population. There are several relevant clinical and pathological considerations when they are both diagnosed in the same eye.
methodsWe systematically searched the literature to review the challenges clinicians must address when dealing with patients with co-existing PMM and glaucoma.
resultsAlthough the current literature is limited there appears to be a link between the occurrence of glaucomatous optic neuropathy and idiopathic PMM. The presence of PMM can confound glaucomatous progression detection on optical coherence tomography (OCT). Vitrectomy and membrane peeling may improve vision in some patients with co-existing disease but there may be an increased risk of glaucoma progression particularly in eyes with advanced glaucoma and more extensive neuronal loss. Peeling of the retinal inner limiting membrane in addition to PMM peeling may result in an increased risk of visual loss. Inner nuclear layer hypo-reflective spaces on OCT are particularly prevalent in eyes with glaucoma and PMM and may be a negative prognostic sign for outcome.
conclusionPatients should be counseled regarding the guarded prognosis, and careful consideration given to the benefits of PMM surgery. Further research is needed to guide clinical practice.
Indexed as
Identifiers
40080208What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.