ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2025
Patient-reported outcomes in head and neck cancer: a cross-sectional analysis of quality of life domains across early and advanced UICC stages.
Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Responsiveness and clinical utility of patient-reported outcome instruments in head and neck cancer: a systematic review.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026Pooled it
- A Qualitative Study of Patient and Caregiver Perspectives on Locally Advanced Head and Neck Cancer in the United States.Oncology and therapy · 2026Article
- Quality of life and associated factors among cancer patients receiving palliative care in Western Uganda: a cross-sectional study.BMC palliative care · 2026Article
- Out-of-Pocket Costs and Antidepressant Adherence in Head and Neck Cancer Survivors.Psycho-oncology · 2026Article
- Patient Satisfaction and Supportive Care Pathways in a German Head and Neck Tumor Center: A Prospective Cross-Sectional Study.Healthcare (Basel, Switzerland) · 2026Article
- Dynamic changes in symptom clusters and their influencing factors in oral cancer patients throughout the treatment cycle: a longitudinal study based on principal component analysis and linear mixed-effects modeling.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Article
- Alcohol-Related Risk, Depressive Symptoms, HRQoL, and Coping Phenotypes in Head-and-Neck Cancer: A Multicenter Cross-Sectional Study Stratified by Clinical Stage.Medicina (Kaunas, Lithuania) · 2026Observational
- Validation of the Tamil Version of the Taste and Smell Questionnaire for Assessing Sensory Dysfunction in Head and Neck Cancer Patients Undergoing Chemoradiotherapy.Asian Pacific journal of cancer prevention : APJCP · 2026Article
- Unmet supportive care needs among head and neck cancer survivors in China: multicenter cross-sectional study.Frontiers in public health · 2026Article
- Consequences of interrupted follow-up in head and neck cancer and oral potentially malignant disorders patients due to the COVID-19 pandemic.Medicina oral, patologia oral y cirugia bucal · 2026Article
- Cancer treatment fatigue and nutritional awareness in cancer patients: a latent profile analysis and predictors.Frontiers in nutrition · 2026Article
Corrections and comments
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Authors and funding
15 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHead and neck cancer (HNC) patients experience a variety of post-treatment symptoms that affect their quality of life (QoL). This study aims to assess the most prevalent symptoms and their relationship to cancer stage (UICC I-IV) while identifying areas for targeted intervention.
methodsA cross-sectional study was conducted involving 340 HNC patients at the University Hospital Erlangen from January to December 2019. QoL and its domains were assessed using the German version of the University of Washington Quality of Life Questionnaire Version 4 (UW-QoL v.4), with comparisons made between early-stage (UICC I & II, n = 180) and advanced-stage (UICC III & IV, n = 160) patients. Statistical analysis examined differences in QoL and its individual domains.
resultsAdvanced-stage patients reported significantly greater impairments in several QoL domains, including swallowing (p = 0.003, η
conclusionAdvanced-stage HNC patients experience a significantly higher burden of physical symptoms, particularly issues with swallowing, saliva, and taste, necessitating early and targeted interventions. Psychological issues are also prevalent and should be addressed in both early- and advanced-stage patients. Despite non-significant differences in some symptoms, their clinical relevance may still be important, particularly in individual cases. Comprehensive care, including physical and emotional support, is essential to improving long-term QoL for HNC patients. Further research should focus on longitudinal assessments and clinically meaningful thresholds for symptom management.
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