ArticleFish physiology and biochemistry2025
Carbonate alkalinity induces stress responses and renal and metabolic disorders in Nile tilapia: mitigation by camel whey protein hydrolysate diet.
Article in Fish physiology and biochemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
- Oxidative Stress in Aquaculture: Pathogenic Mechanisms and Preventive Strategies in Farmed Aquatic Animals.Current issues in molecular biology · 2025Review
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9 authors.
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Abstract
Alkaline stress is a major concern in aquaculture that badly affects the aquatic species' health and hemostasis. This research investigated the effect of carbonate alkalinity exposure on the gills and kidney organs as important organs for hemostasis, as well as the ameliorative role of camel protein hydrolysates (CPH) as dietary additives against alkaline stress detrimental impacts in Nile tilapia (Oreochromis niloticus). The fish (n = 160) were divided into four groups (G1, G2, G3, and G4), with the control (G1) fed a basal diet, while G2 was fed a basal diet supplemented with 75 g CPH/kg and was reared in freshwater (carbonate alkalinity of 1.4 µmol/L, pH = 7.19). The G3 and G4 were reared in alkaline water (carbonate alkalinity of 23.8 µmol/L, pH = 8.65) and fed the same diets as G1 and G2 for 30 days, respectively. The fish were stocked under a water temperature of 26.4 ± 1.5 °C, and the diets were introduced to the fish three times daily at a rate of 4% of their body weight. The results of this research showed that alkaline exposure increased kidney function parameters (creatinine, urea, and uric acid), glucose, and cortisol levels in the exposed fish. Alkaline exposure reduced the blood electrolytes level (calcium, magnesium, sodium, potassium, and chloride) and branchial antioxidant enzymes (superoxide dismutase, catalase, glutathione peroxidase, and reduced glutathione) and elevated malondialdehyde level in the exposed fish. Significant downregulation of the branchial expression of Na
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