Evidence map›Paper›PMID 40080142›Full record

ArticleArchives of virology2025

Molecular insights from 2023 and 2024 outbreaks reveal exclusive circulation of peste des petits ruminants virus lineage IV in India.

Asha Anand, Swathi Mahadevappa, Rakshit Ojha, Archana Pal, Shweta Priya, Annett Helcita Dsouza, Prajakta Prashant Bokade, Kirubakaran Vinod Kumar, Divakar Hemadri, Baldev Raj Gulati and 1 more

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Article in Archives of virology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Asha Anand *ICAR-National Institute of Veterinary Epidemiology and Disease Informatics (NIVEDI), Yelahanka, 560 119, Bengaluru, Karnataka, India.
Swathi Mahadevappa *ICAR-National Institute of Veterinary Epidemiology and Disease Informatics (NIVEDI), Yelahanka, 560 119, Bengaluru, Karnataka, India.
Rakshit OjhaICAR-National Institute of Veterinary Epidemiology and Disease Informatics (NIVEDI), Yelahanka, 560 119, Bengaluru, Karnataka, India.
Archana PalICAR-National Institute of Veterinary Epidemiology and Disease Informatics (NIVEDI), Yelahanka, 560 119, Bengaluru, Karnataka, India.
Shweta PriyaICAR-National Institute of Veterinary Epidemiology and Disease Informatics (NIVEDI), Yelahanka, 560 119, Bengaluru, Karnataka, India.
Annett Helcita DsouzaICAR-National Institute of Veterinary Epidemiology and Disease Informatics (NIVEDI), Yelahanka, 560 119, Bengaluru, Karnataka, India.
Prajakta Prashant BokadeICAR-National Institute of Veterinary Epidemiology and Disease Informatics (NIVEDI), Yelahanka, 560 119, Bengaluru, Karnataka, India.
Kirubakaran Vinod KumarICAR-National Institute of Veterinary Epidemiology and Disease Informatics (NIVEDI), Yelahanka, 560 119, Bengaluru, Karnataka, India.
Divakar HemadriICAR-National Institute of Veterinary Epidemiology and Disease Informatics (NIVEDI), Yelahanka, 560 119, Bengaluru, Karnataka, India.
Baldev Raj GulatiICAR-National Institute of Veterinary Epidemiology and Disease Informatics (NIVEDI), Yelahanka, 560 119, Bengaluru, Karnataka, India.
Vinayagamurthy BalamuruganICAR-National Institute of Veterinary Epidemiology and Disease Informatics (NIVEDI), Yelahanka, 560 119, Bengaluru, Karnataka, India. b.vinayagamurthy@icar.gov.in.ORCID http://orcid.org/0000-0001-7821-7427

Funding

DAHD K-11053(5313)/21/2019-LH (E-14082)
6 · The paper itself

Abstract

Peste des petits ruminants (PPR) is a highly contagious disease affecting sheep and goats, caused by PPR virus (PPRV), a member of the genus Morbillivirus. In 2023 and 2024, on testing of suspected clinical samples for PPR received through passive surveillance of sheep and goat flocks in various states of India resulted in the documentation of 15 laboratory-confirmed outbreaks of PPR. During the outbreak investigation, morbidity and significant mortality rates were observed, and clinical samples collected from the affected flocks were tested using ELISA and RT-PCR, confirming the presence of PPRV. We studied in detail nine out of 15 confirmed outbreaks for characterization of virus including partial sequencing of nucleocapsid (N) and fusion (F) genes of the PPRV. In addition, the virus from each outbreak was isolated from tissue and swab samples by blind passage in Vero cells. Phylogenetic analysis based on partial N gene sequences revealed that all of the Indian isolates belonged to Asian lineage IV. This study confirms that all of the cases of PPR reported so far in India have been caused by PPRV lineage IV.

Indexed as

Disease OutbreaksGoat DiseasesPeste-des-Petits-RuminantsPeste-des-petits-ruminants virusSheep DiseasesAnimalsChlorocebus aethiopsGoatsIndiaNucleocapsid ProteinsPhylogenySheepVero CellsNucleocapsid ProteinsIndialineage IVN geneoutbreaksphylogenyPPRVRT-PCRVero cells

Identifiers

PMID40080142

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.