Evidence map›Paper›PMID 40080129›Full record

ArticleInternational orthopaedics2025

Anatomical variations and their association with carpal tunnel syndrome: a comparison with healthy controls.

Michaela Gruber, Agnes Wawrik, Florin Gasser, Barbara Ebner, Philipp Reitbauer, Robert Uzel, Rodolphe Poupardin, Maximilian Mahrhofer, Laurenz Weitgasser, Karl Schwaiger and 3 more

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in International orthopaedics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

13 authors.

Michaela GruberHospital of the Brothers of St. John of God, Salzburg, Austria.
Agnes WawrikHospital of the Brothers of St. John of God, Salzburg, Austria.
Florin GasserHospital of the Brothers of St. John of God, Salzburg, Austria.
Barbara EbnerHospital of the Brothers of St. John of God, Salzburg, Austria.
Philipp ReitbauerHospital of the Brothers of St. John of God, Salzburg, Austria.
Robert UzelHospital of the Brothers of St. John of God, Salzburg, Austria.
Rodolphe PoupardinParacelsus Medical University, Salzburg, Austria.
Maximilian MahrhoferHospital of the Brothers of St. John of God, Salzburg, Austria.
Laurenz WeitgasserHospital of the Brothers of St. John of God, Salzburg, Austria.
Karl SchwaigerHospital of the Brothers of St. John of God, Salzburg, Austria.
Gottfried SchafflerHospital of the Brothers of St. John of God, Salzburg, Austria.
Gottfried WechselbergerHospital of the Brothers of St. John of God, Salzburg, Austria.
Elisabeth RusseHospital of the Brothers of St. John of God, Salzburg, Austria. elisabeth.russe@bbsalz.at.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe prevalence of carpal tunnel syndrome (CTS) as the foremost upper extremity entrapment neuropathy is well-documented. The present study aimed to evaluate the prevalence of anatomical variations in the carpal tunnel and their potential role as risk factors for CTS.

methodsData from 447 CTS patients who underwent median nerve decompression between 2018 and 2019 were retrospectively analyzed. As a control group, 200 hands from 103 age- and sex-matched asymptomatic volunteers were further investigated.

resultsAnatomical variations identified through ultrasound in 19.7% of CTS hands and 16.0% of controls. Specifically, 10.3% of CTS hands had persistent median arteries, while 14.3% had bifid median nerves. Both variations occurred in 4.9% of CTS patients. In the control group, 13.0% had persistent median arteries and 11.0% had bifid median nerves, with both found in 8.0%.

conclusionsAnatomical variations were found in both, CTS patients and controls, but their prevalence did not differ significantly between groups, suggesting they are not independent risk factors for CTS.

Indexed as

Anatomic VariationCarpal Tunnel SyndromeMedian NerveAdultAgedCase-Control StudiesDecompression, SurgicalFemaleHumansMaleMiddle AgedPrevalenceRetrospective StudiesRisk FactorsUltrasonographyAnatomical variationsBifid median nerveCarpal tunnel syndromePersistent arteria medianaPersistent median arteryUltrasound

Identifiers

PMID40080129

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