Evidence map›Paper›PMID 40080092›Full record

ReviewNephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association2025

Cognitive impairment in chronic kidney disease: role of brain imaging, functional imaging, electroencephalography, cerebrospinal fluid biomarkers and sensors.

Alexandre Andrade, Maie Bachmann, Mickaël Bobot, Annette Bruchfeld, Ivo Fridolin, Laila-Yasmin Mani, Hong Xu, CONNECT Action (Cognitive Decline in Nephro-Neurology European Cooperative Target) collaborators

Abstract readReview
In one paragraph

Review in Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Alexandre AndradeInstituto de Biofísica e Engenharia Biomédica, Faculdade de Ciências da Universidade de Lisboa, Lisboa, Portugal.ORCID 0000-0002-8107-7338
Maie BachmannDepartment of Health Technologies, School of Information Technologies, Tallinn University of Technology, Tallinn, Estonia.
Mickaël BobotCentre de Néphrologie et Transplantation Rénale, Hôpital de la Conception, AP-HM C2VN, INSERM 1263, INRAE 1260, CERIMED, Aix-Marseille Université, Marseille, France.ORCID 0000-0002-9451-0372
Annette BruchfeldDepartment of Health, Medicine and Caring Sciences, Linköping University, Linköping, Sweden.ORCID 0000-0002-9752-9941
Ivo FridolinDepartment of Health Technologies, School of Information Technologies, Tallinn University of Technology, Tallinn, Estonia.
Laila-Yasmin ManiDepartment of Nephrology and Hypertension, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.ORCID 0000-0002-4693-7814
Hong XuDivision of Clinical Geriatrics, Department of Neurobiology, Care Sciences and Society (NVS), Karolinska Institutet, Stockholm, Sweden.ORCID 0000-0002-7266-3431
CONNECT Action (Cognitive Decline in Nephro-Neurology European Cooperative Target) collaborators

Funding

COST CA19127Estonian Research Council TK218Fundação para a Ciência e a Tecnologia UIDB/00645/2020
6 · The paper itself

Abstract

Chronic kidney disease is associated with cognitive impairment although the underlying mechanisms are still not fully understood. Characterization and efficient monitoring of the cognitive impact of kidney disease and ensuing therapies are critical for the accurate clinical management of patients. A vast array of imaging modalities, biomarkers, and sensors have shown relevance for the assessment of cognitive impairment. Knowing the potential and limitations of these paraclinical techniques is a necessary condition to improve the understanding of this phenomenon and to design monitoring protocols and guidelines applicable to this clinical population. The goal of this review is to provide an overview of current imaging modalities and biomarker sources available to the community, for the benefit of the research and clinical community.

Indexed as

BiomarkersBrainCognition DisordersElectroencephalographyRenal Insufficiency, ChronicHumansNeuroimagingBiomarkersbrain imagingCKDCSF biomarkersEEGfunctional imaging

Identifiers

PMID40080092
PMCPMC11997786

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.