Evidence map›Paper›PMID 40080090›Full record

ReviewNephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association2025

Cognitive impairment in kidney transplanted patients.

Jolanta Malyszko, Aleksandra Golenia, Michele Farisco, Vincenzina Lo Re, Aleksandra Klimkowicz-Mrowiec, Giovambattista Capasso, Dimitris Goumenos, Merita Rroji, Andreja Figurek, Gaye Hafez and 1 more

Abstract readReview
In one paragraph

Review in Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Observational
  5. Article
  6. Article
  7. Article
  8. Article
  9. The Critical Role of Mental Health Specialists in Organ Transplantation Teams: An ELPAT Position Statement.Transplant international : official journal of the European Society for Organ Transplantation · 2026
    Article
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jolanta MalyszkoDepartment of Nephrology, Dialysis and Internal Medicine, Warsaw Medical University, Warsaw, Poland.
Aleksandra GoleniaDepartment of Neurology, Warsaw Medical University, Warsaw, Poland.
Michele FariscoBiogem Molecular Biology and Genetics Research Institute, Ariano Irpino (AV), Italy.ORCID 0000-0002-3298-7829
Vincenzina Lo ReNeurology Service, Department of Diagnostic and Therapeutic Services, IRCCS-ISMETT/UPMC, Palermo, Italy.
Aleksandra Klimkowicz-MrowiecDepartment of Internal Diseases and Gerontology, Jagiellonian University, College of Medicine, Krakow, Poland.
Giovambattista CapassoBiogem Molecular Biology and Genetics Research Institute, Ariano Irpino (AV), Italy.ORCID 0000-0001-8701-8171
Dimitris GoumenosDepartment of Nephrology and Renal Transplantation, Patras University Hospital, Patras, Greece.
Merita RrojiUniversity Department of Nephrology, Faculty of Medicine, University of Medicine Tirana, Tirana 1001, Albania.ORCID 0000-0003-1048-2579
Andreja FigurekInstitute of Anatomy, University of Zurich, Zurich 8057, Switzerland.
Gaye HafezDepartment of Pharmacology, Faculty of Pharmacy, Altinbas University, Istanbul, Turkey.
CONNECT Action (Cognitive Decline in Nephro-Neurology European Cooperative Target) collaborators

Funding

COST CA19127
6 · The paper itself

Abstract

Chronic kidney disease affects almost all of the organs. Recently, more attention has been paid to the kidney and the central nervous system connections. In patients on kidney replacement therapy, including kidney transplantation, there is an increased prevalence of cognitive impairment, and depression and other neurological complications, such as cerebrovascular disorders and movement disorders. Kidney transplant recipients need an assessment for the risk factors and the pattern of cognitive impairment (memory, attention and executive function decline). This enables an accurate diagnosis to be made at an earlier stage. Partial post-transplant cognitive impairment recovery is also important. Finally, doctors and patients alike face numerous ethical concerns and challenges regarding the transplantation of kidneys and other solid organs. In this review, we examined some key issues regarding cognitive impairment in kidney transplant patients. We focused on the mechanism of cognitive impairment in kidney transplant recipients, patterns of cognitive impairment; evaluation of patients with cognitive impairment for kidney transplantation, the potential impact of cognitive impairment on waitlisted and transplanted patients on patient care, non-pharmacological interventions and unmet medical needs, psychological and ethical issues in kidney transplantation, and unmet needs. As cognitive impairment in kidney transplant recipients is an underestimated, underrecognized but clinically relevant problem, screening for cognitive function before and after kidney transplantation would be worth considering in standard routine practice.

Indexed as

Cognition DisordersCognitive DysfunctionKidney TransplantationHumansPrognosisRisk Factorschronic kidney diseasecognitive impairmentethicskidney transplantationpsychological issues

Identifiers

PMID40080090
PMCPMC11905761

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.