Evidence map›Paper›PMID 40079925›Full record

ArticleInternational braz j urol : official journal of the Brazilian Society of Urology

Novel Role Of DSNB in Staging of Primary Urethral Cancer: New Standard?

Adnan Fazili, R Barry Sirard, Laura Elst, Kaat Vandermaesen, Hongzhi Xu, Maarten Albersen, Philippe E Spiess

Abstract read
In one paragraph

Article in International braz j urol : official journal of the Brazilian Society of Urology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. LaparoscopicGynecology and pelvic medicine · 2026
    Article
  3. Telesurgery in Urology is the Hot Topic in this Number of International Brazilian Journal of Urology.International braz j urol : official journal of the Brazilian Society of Urology
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Adnan FaziliDepartment of Genitourinary Oncology, H. Lee Moffitt Cancer Center, Tampa, FL, USA.
R Barry SirardUniversity of South Florida Morsani College of Medicine, Tampa, FL, USA.
Laura ElstDepartment of Urology, University Hospitals Leuven, Leuven, Belgium.
Kaat VandermaesenDepartment of Urology, University Hospitals Leuven, Leuven, Belgium.
Hongzhi XuDepartment of Genitourinary Oncology, H. Lee Moffitt Cancer Center, Tampa, FL, USA.
Maarten AlbersenDepartment of Urology, University Hospitals Leuven, Leuven, Belgium.
Philippe E SpiessDepartment of Genitourinary Oncology, H. Lee Moffitt Cancer Center, Tampa, FL, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We describe the novel use of dynamic sentinel node biopsy (DSNB) in five patients with primary urethral squamous cell carcinoma (U-SCC) and no evidence of inguinal node disease across two centers in North America and Europe between 03/2021 and 06/2024. Each of these referral centers sees over 75 cases of penile cancer per year and approximately 10 cases of U-SCC per year. Patients underwent DSNB concomitant to surgical resection of the primary tumor (n=3), or in a deferred manner (n=2), six weeks after primary surgery. In the five DSNBs performed, clinically occult nodal metastasis was discovered in one patient. In this patient DSNB was performed after local recurrence and repeat imaging confirming cN0 status. Only one minor complication with DSNB was observed. Awaiting further investigations in larger series, this study highlights the feasibility of DSNB in primary U-SCC with clinically node negative disease.

Indexed as

Carcinoma, Squamous CellSentinel Lymph Node BiopsyUrethral NeoplasmsAgedFeasibility StudiesHumansLymphatic MetastasisMaleMiddle AgedNeoplasm StagingSentinel Lymph Node BiopsyUrethral Neoplasms

Identifiers

PMID40079925
PMCPMC12052031

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.