Evidence map›Paper›PMID 40079811›Full record

Observational studyClinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis

Safety and Efficacy of the Use of pdVWF/FVIII-C in Patients with von Willebrand Disease: A Prospective, Observational, Post-Authorization Study.

Olga Benítez Hidalgo, Cristina Marzo Alonso, Francisco José López Jaime, Marina Carrasco, Maria Del Mar Nieto Hernández, Natalia Afonso, Alejhandra Lei, Dermot Whyms, Kim Hanna, Maria Esperança Aragonés and 2 more

Abstract readObservational StudyMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Olga Benítez HidalgoHematology Department, Hospital Universitari Vall d'Hebron, Barcelona, Spain.
Cristina Marzo AlonsoHematology and Hemotherapy Service, Hospital Universitari Arnau de Vilanova, Lleida, Spain.
Francisco José López JaimeHemostasis and Thrombosis Unit, Hospital Regional Universitario de Málaga, Málaga, Spain.
Marina CarrascoThrombosis and Hemostasis Unit, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.
Maria Del Mar Nieto HernándezHematology and Hemotherapy Service, Complejo Universitario de Jaén, Jaén, Spain.
Natalia AfonsoScientific Innovation Office, Grifols, Barcelona, Spain.
Alejhandra LeiScientific Innovation Office, Grifols, Barcelona, Spain.
Dermot WhymsScientific Innovation Office, Grifols, Research Triangle Park, NC, USA.
Kim HannaScientific Innovation Office, Grifols, Research Triangle Park, NC, USA.
Maria Esperança AragonésScientific Innovation Office, Grifols, Barcelona, Spain.
Mireia TorresScientific Innovation Office, Grifols, Barcelona, Spain.
Juan OliverasScientific Innovation Office, Grifols, Barcelona, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

IntroductionPlasma-derived von Willebrand factor containing FVIII concentrates (pdVWF/FVIII-C) are indicated as replacement therapy for patients with von Willebrand disease (VWD). This study assessed safety and efficacy associated with long-term real-world experience of the pdVWF/FVIII-C, Fanhdi

Indexed as

Factor VIIIvon Willebrand Diseasesvon Willebrand FactorAdolescentAdultAgedDrug CombinationsFemaleHemorrhageHumansMaleMiddle AgedProspective StudiesTreatment OutcomeYoung AdultDrug CombinationsFactor VIIIfactor VIII, von Willebrand factor drug combinationvon Willebrand Factorbleedinginvasive procedureson-demand treatmentplasma-derived von Willebrand factor/factor VIII concentrateprophylaxis treatmentreal world evidencesurgeryvon Willebrand disease

Identifiers

PMID40079811
PMCPMC11907537

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.