Evidence map›Paper›PMID 40079798›Full record

ReviewClinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis

Diagnosis of Antiphospholipid Syndrome by Chemiluminescent or Enzyme-Linked Immunosorbent Assay - A Comparison Study and Comprehensive Literature Review.

Eunice E N Lai, Cheryl X Q Lim, Jacqueline P J Lau, Yen Lin Chee, Stephrene S W Chan, Winnie Z Y Teo, Eng Soo Yap, Shir Ying Lee

Abstract readComparative StudyReview
In one paragraph

Review in Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Eunice E N LaiDepartment of Haematology-Oncology, National University Cancer Institute, National University Hospital, Singapore, Singapore.ORCID 0009-0009-5632-522X
Cheryl X Q LimDepartment of Haematology-Oncology, National University Cancer Institute, National University Hospital, Singapore, Singapore.
Jacqueline P J LauDivision of Haematology, Department of Laboratory Medicine, National University Hospital, Singapore, Singapore.ORCID 0009-0007-5332-4577
Yen Lin CheeDepartment of Haematology-Oncology, National University Cancer Institute, National University Hospital, Singapore, Singapore.ORCID 0000-0002-8176-8382
Stephrene S W ChanDepartment of Haematology-Oncology, National University Cancer Institute, National University Hospital, Singapore, Singapore.ORCID 0000-0003-4828-6303
Winnie Z Y TeoDepartment of Haematology-Oncology, National University Cancer Institute, National University Hospital, Singapore, Singapore.ORCID 0000-0003-4356-6146
Eng Soo YapDivision of Haematology, Department of Laboratory Medicine, National University Hospital, Singapore, Singapore.ORCID 0000-0002-7910-3154
Shir Ying LeeDepartment of Haematology-Oncology, National University Cancer Institute, National University Hospital, Singapore, Singapore.ORCID 0000-0002-5119-8753

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

ObjectiveEnzyme-linked immunosorbent assay (ELISA) is the established method for detecting antiphospholipid antibodies (aPL) in the diagnosis of antiphospholipid syndrome (APS) but is labor-intensive compared with the newer automated chemiluminescent assay (CLIA). This study aims to evaluate CLIA versus ELISA for aPL, correlate each method with clinical manifestations and perform a comprehensive literature review.MethodsPatient samples were concurrently tested by ELISA (QUANTA Lite

Indexed as

Antibodies, AntiphospholipidAntiphospholipid SyndromeLuminescent MeasurementsAdultEnzyme-Linked Immunosorbent AssayFemaleHumansMaleMiddle AgedAntibodies, Antiphospholipidantiphospholipid antibodiesantiphospholipid syndromechemiluminescentdiagnosisELISAsolid phase assay

Identifiers

PMID40079798
PMCPMC11907618

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.