ArticleChemistry, an Asian journal2025
Kinetic Control of Threading and Dethreading in Linked Rotaxanes via Hydrogen Bonding.
Article in Chemistry, an Asian journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Kinetic Control of Threading and Dethreading in Linked Rotaxanes via Hydrogen Bonding.Chemistry, an Asian journal · 2025Article
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Authors and funding
5 authors.
Funding
Abstract
The kinetic control of macrocyclic motions is a key aspect of mechanically interlocked molecules (MIMs). Although hydrogen bonding (H-bonding) offers a high reversibility and selectivity, the use of neutral H-bonding to control the macrocyclic mobility remains limited. In this study, the effects of H-bonding on the threading and dethreading kinetics of linked rotaxanes containing a permethylated α-cyclodextrin unit and an aniline moiety were investigated. UV-vis spectroscopy revealed significantly reduced reaction rates in H-bond acceptor solvents, such as dimethyl sulfoxide (DMSO) and N,N-dimethyl formamide. NMR titrations and FT-IR spectroscopic analyses confirmed that H-bonding between the aniline moiety and these solvents acts as a "brake" during threading/dethreading. Moreover, Eyring plots indicated that enthalpic losses during H-bond cleavage contribute to the increased activation barriers for these processes. Additionally, the introduction of H-bond acceptors, such as DMSO and tributylphosphine oxide, effectively modulated these rates of threading and dethreading, highlighting the potential for controlling kinetic phenomena in MIM-based systems.
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Registered trials
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