Evidence map›Paper›PMID 40079344›Full record

ArticleJournal of the American Heart Association2025

Gestational and Early Childhood Exposure to Barium and Cardiometabolic Risk in Preschoolers: Findings From the Ma'anshan Birth Cohort Study in China.

Juan Tong, Xing Wang, Hong Gan, Hui Gao, Mengjuan Lu, Jixing Zhou, Chunmei Liang, Shuman Tao, Menglong Geng, Shuangqin Yan and 5 more

Abstract read
In one paragraph

Article in Journal of the American Heart Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Juan TongDepartment of Maternal, Child and Adolescent Health, School of Public Health Anhui Medical University Hefei Anhui China.
Xing WangDepartment of Maternal, Child and Adolescent Health, School of Public Health Anhui Medical University Hefei Anhui China.
Hong GanDepartment of Maternal, Child and Adolescent Health, School of Public Health Anhui Medical University Hefei Anhui China.
Hui GaoDepartment of Maternal, Child and Adolescent Health, School of Public Health Anhui Medical University Hefei Anhui China.
Mengjuan LuDepartment of Maternal, Child and Adolescent Health, School of Public Health Anhui Medical University Hefei Anhui China.
Jixing ZhouDepartment of Maternal, Child and Adolescent Health, School of Public Health Anhui Medical University Hefei Anhui China.
Chunmei LiangDepartment of Maternal, Child and Adolescent Health, School of Public Health Anhui Medical University Hefei Anhui China.ORCID 0000-0003-1639-7543
Shuman TaoDepartment of Maternal, Child and Adolescent Health, School of Public Health Anhui Medical University Hefei Anhui China.
Menglong GengDepartment of Maternal, Child and Adolescent Health, School of Public Health Anhui Medical University Hefei Anhui China.ORCID 0000-0003-3252-1460
Shuangqin YanMa'anshan Maternal and Child Health Care Hospital Ma'anshan Anhui China.
Guopeng GaoMa'anshan Maternal and Child Health Care Hospital Ma'anshan Anhui China.ORCID 0009-0004-3376-6552
Xueqing WangMa'anshan Maternal and Child Health Care Hospital Ma'anshan Anhui China.
Kun HuangDepartment of Maternal, Child and Adolescent Health, School of Public Health Anhui Medical University Hefei Anhui China.ORCID 0000-0001-8550-4571
Xiaoyan WuDepartment of Maternal, Child and Adolescent Health, School of Public Health Anhui Medical University Hefei Anhui China.ORCID 0009-0003-7802-9882
Fangbiao TaoDepartment of Maternal, Child and Adolescent Health, School of Public Health Anhui Medical University Hefei Anhui China.ORCID 0000-0003-4807-9670

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAnimal studies suggest cardiovascular systems may be primary targets for barium toxicity. This study aims to examine longitudinal associations of prenatal and early childhood barium exposure with cardiometabolic risk (CMR) in preschoolers. METHODS AND

resultsWe determined serum or plasma barium concentrations during 3 trimesters, delivery, and early childhood (5 years) from 2291 mother-child dyads within the Ma'anshan Birth Cohort. CMR scores were calculated by summing standardized

conclusionsBarium exposure during pregnancy, especially during the second and third trimesters, may increase CMR in preschoolers. Boys are more vulnerable than girls. These findings support the need for reductions in barium exposure during pregnancy.

Indexed as

BariumPrenatal Exposure Delayed EffectsAdultBlood GlucoseCardiometabolic Risk FactorsChild, PreschoolChinaFemaleHumansMalePregnancyRisk AssessmentBariumBlood Glucosebariumcardiometabolic riskcohortearly‐childhoodprenatal

Identifiers

PMID40079344
PMCPMC12132787

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.