ArticleThe Journal of infectious diseases2025
A Diagnostic Approach to Separate Acute Human Bocavirus 1 Respiratory Tract Infection From Long-lasting Virus Shedding.
Article in The Journal of infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- Metagenomic sequencing identifies potential respiratory pathogens in PCR-negative subset of surveillance samples.Scientific reports · 2026Article
- Twenty years of human bocavirus research: from an unculturable virus of unclear pathogenicity to a culturable human pathogen and gene therapy vector candidate.Clinical microbiology reviews · 2025Review
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
Human bocavirus 1 (HBoV1) causes mild to life-threatening respiratory tract infections in children but may persist in the airways for months. Currently used polymerase chain reaction may thus lead to false diagnoses and irrelevant codetections. Our aim was to differentiate acute infections from persistent shedding by pretreatment of airway or serum samples with an endonuclease, followed by polymerase chain reaction (ePCR). We show that HBoV1 DNA is protected by a capsid in the acute phase but not in persistent shedding, and we provide proof of concept of a novel test that may be applied in routine diagnosis of acute HBoV1 respiratory tract infection for more accurate results.
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Registered trials
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