Evidence map›Paper›PMID 40079297›Full record

ArticleJournal of the American Heart Association2025

Years of Potential Life Lost for Children and Adults With Congenital Heart Defects: United States, 2007 to 2017.

Wendy N Nembhard, Suman Maity, Emine Bircan, Maria D Politis, Elijah H Bolin, Jun Ying

Abstract read
In one paragraph

Article in Journal of the American Heart Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trends in congenital heart disease mortality in the United States from 1968 to 2022.International journal of cardiology. Congenital heart disease · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Wendy N NembhardDepartment of Epidemiology, Fay W. Boozman College of Public Health University of Arkansas for Medical Sciences Little Rock AR USA.ORCID 0000-0002-8318-4049
Suman MaityDepartment of Epidemiology, Fay W. Boozman College of Public Health University of Arkansas for Medical Sciences Little Rock AR USA.ORCID 0000-0002-2317-536X
Emine BircanDepartment of Epidemiology, Fay W. Boozman College of Public Health University of Arkansas for Medical Sciences Little Rock AR USA.ORCID 0000-0003-2527-3470
Maria D PolitisArkansas Center for Birth Defects Research and Prevention, Fay W. Boozman College of Public Health University of Arkansas for Medical Sciences Little Rock AR USA.ORCID 0000-0002-7511-8383
Elijah H BolinArkansas Center for Birth Defects Research and Prevention, Fay W. Boozman College of Public Health University of Arkansas for Medical Sciences Little Rock AR USA.ORCID 0000-0002-6805-2611
Jun YingArkansas Center for Birth Defects Research and Prevention, Fay W. Boozman College of Public Health University of Arkansas for Medical Sciences Little Rock AR USA.ORCID 0000-0002-7693-4243

Funding

NCBDD CDC HHS U01 DD001227NCBDD CDC HHS U01 DD001304
6 · The paper itself

Abstract

backgroundAlthough most children with congenital heart defects (CHDs) live into adulthood, many have increased mortality risk across the lifespan. Little is known about years lost due to premature CHD-related deaths. We estimated the years of potential life lost (YPLL) among individuals with CHDs in the United States.

methodsWe used 2007 to 2017 death records from the US National Center for Health Statistics to identify decedents with a CHD listed as the underlying or contributing cause of death. We calculated the average percent change in YPLL and the total, mean, crude, and age-standardized YPLL overall, by sex, race and ethnicity, and age group.

resultsOf 28.35 million deaths, 42 158 were CHD-related. The premature deaths attributed to CHD for individuals younger than 65 years was almost 2.1 million years; of those 169 756 and 124 067 years were lost prematurely for children and adolescents, respectively. Men and women with CHDs had 1.13 million and 941 115 years lost prematurely, respectively. Non-Hispanic Black individuals and men had the highest age-standardized YPLL (per 100 000) (95.5 [95% CI, 93.2-97.7] and 74.1 [95% CI, 73.0-75.1]). The overall mean YPLL was 70 years (per 100 000) and non-Hispanic Black men and women had the highest mean YPLL. During 2007 to 2017, the YPLL average percent change declined by 17.8% overall, but the YPLL for non-Hispanic Black individuals aged 1 to 4 years (-31.6%) and 35 to 49 years (-24.3%) had the greatest decline.

conclusionsChildren with CHDs experience significant premature deaths. Non-Hispanic Black and male individuals experienced the highest burden of premature deaths associated with CHDs. Further research is needed to elucidate these disparities.

Indexed as

Heart Defects, CongenitalLife ExpectancyAdolescentAdultAgedAge FactorsCause of DeathChildChild, PreschoolFemaleHumansInfantInfant, NewbornMaleMiddle AgedMortality, Prematurecongenital heart defectshealth disparitymortalitypremature deathracial or ethnicyears of potential life lost

Identifiers

PMID40079297
PMCPMC12132721

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.