SynthesisCancer medicine2025
Perioperative Trends in Distress Among Cancer Patients: A Systematic Review and Meta-Analysis.
Synthesis in Cancer medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Perioperative Depressive Symptoms in Surgical Cancer Patients: a Systematic Review and Meta-analysis.Annals of surgical oncology · 2026Pooled it
- Esketamine for Postoperative Anxiety After Major Abdominal Tumor Surgery: A Randomized Clinical Trial.Drug design, development and therapy · 2026Trial
- The mediating role of illness perception between Type D personality and psychological distress in preoperative patients with gynecologic cancers: A cross-sectional study.Asia-Pacific journal of oncology nursing · 2026Article
- Perioperative psycho-behavioral stress promotes cancer metastasis beyond the impact of surgery: Neuroendocrine and tumor molecular mediating mechanisms.Brain, behavior, & immunity - health · 2026Article
- Effects of Glioblastoma Resection on Cognitive Function and Affective Symptoms at Three-Month Follow-Up.Brain and behavior · 2026Observational
- Navigating emotional and professional challenges: Israeli nurses' experiences in breast cancer surgery preparation.BMC nursing · 2026Article
- Perioperative symptom burden as an independent predictor of long-term functional and survival outcomes in oral squamous cell carcinoma patients undergoing free flap reconstruction: a retrospective cohort study.American journal of cancer research · 2026Article
- Cervical chordoma en bloc resection and staged suprascapular nerve transfer reanimation: illustrative case.Journal of neurosurgery. Case lessons · 2025Article
- Psychological distress, body image, and nutritional status during hospitalization for gynecological cancer surgery: a prospective observational study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Observational
- Personalizing Patient Education for Pancreatic Cancer Patients Receiving Multidisciplinary Care with Integration of Novel Digital Tools.Healthcare (Basel, Switzerland) · 2025Article
- Natural Orifice Specimen Extraction Surgery yields superior long-term oncological outcomes compared to traditional laparoscopic surgery in stage II-III rectal cancer.American journal of cancer research · 2025Article
Corrections and comments
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Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionDistress is common among cancer patients, especially those undergoing surgery. However, no study has systematically analyzed distress trends in this population. The purpose of this study was to systematically review perioperative rates of distress, as well as differences across cancer types, in cancer patients undergoing surgical intervention.
methodsA systematic review was conducted using PubMed, EMBASE, Scopus, and APA PsycINFO (searched until July 17, 2023). Included studies were clinical studies of cancer patients undergoing surgery reporting distress measured by the National Comprehensive Cancer Network (NCCN) distress thermometer (DT). Data on study and patient characteristics, and preoperative and postoperative distress rates were extracted. Results were pooled, and overall distress rates were calculated as weighted means. Subanalysis by cancer type was performed. Three meta-analyses were conducted: (1) preoperative distress, (2) postoperative distress, and (3) change in distress.
resultsFifty-seven studies including 13,410 cancer patients were reviewed. Most patients were female (67.4%), White (77.8%), and married/partnered (72.2%), with an average age of 59.2 years. The most common cancers were breast (14 studies), brain (8), and colorectal (7). Weighted mean pre- and postoperative distress scores were 5.1 and 4.5, respectively. Distress remained high through 30 days postoperatively, then declined thereafter. Brain cancer patients reported the highest postoperative distress (5.1), followed by breast cancer patients (4.9).
conclusionThe perioperative phase is a critical period of elevated distress in cancer patients. Preoperatively, patients experience moderate to severe levels of distress, which persist throughout the early postoperative phase, gradually declining from the 1-month postoperative mark onwards.
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