Evidence map›Paper›PMID 40079129›Full record

ArticleNucleus (Austin, Tex.)2025

Interplay of replication timing, DNA repair, and translesion synthesis in UV mutagenesis in yeast.

Allysa Sewell, John J Wyrick

Abstract read
In one paragraph

Article in Nucleus (Austin, Tex.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Allysa SewellSchool of Molecular Biosciences, Biotechnology Life Sciences, Washington State University, Pullman, WA, USA.
John J WyrickSchool of Molecular Biosciences, Biotechnology Life Sciences, Washington State University, Pullman, WA, USA.

Funding

Genome-wide analysis of the formation and mutagenesis of atypical UV photoproducts in skin cancerR01ES032814 · NIEHS · WASHINGTON STATE UNIVERSITY · PI STEVEN A ROBERTS, John J Wyrick · 2021 to 2026
$5.8M
Regulation of DNA Excision Repair in ChromatinR01ES028698 · NIEHS · WASHINGTON STATE UNIVERSITY · PI John J Wyrick · 2018 to 2026
$2.7M
Identifying recurrent driver mutations in skin cancers by targeted UV damage sequencingR21ES035139 · NIEHS · WASHINGTON STATE UNIVERSITY · PI WYRICK, JOHN J · 2023 to 2024
$449k
The role of Elf1 in transcription coupled-nucleotide excision repairR21ES035888 · NIEHS · WASHINGTON STATE UNIVERSITY · PI SELVAM, KATHIRESAN, WYRICK, JOHN J · 2024 to 2025
$438k
NIEHS NIH HHS R01 ES028698NIEHS NIH HHS R01 ES032814NIEHS NIH HHS R21 ES035139NIEHS NIH HHS R21 ES035888
6 · The paper itself

Abstract

Replication timing during S-phase impacts mutation rates in yeast and human cancers; however, the exact mechanism involved remains unclear. Here, we analyze the impact of replication timing on UV mutagenesis in

Indexed as

DNA RepairDNA ReplicationDNA Replication TimingMutagenesisSaccharomyces cerevisiaeUltraviolet RaysDNA DamageMutationPyrimidine DimersTranslesion DNA SynthesisPyrimidine DimersComplex mutationsDNA damageglobal genomic-nucleotide excision repairnucleotide excision repairultraviolet light

Identifiers

PMID40079129
PMCPMC11913381

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.