Evidence map›Paper›PMID 40079080›Full record

SynthesisPsychological medicine2025

Prevalence of co-morbid anxiety and depression in pregnancy and postpartum: a systematic review and meta-analysis.

Lu Ou, Quan Shen, Meili Xiao, Weihong Wang, Tan He, Binglu Wang

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Psychological medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Observational
  8. Article
  9. "Journal of clinical medicine · 2026
    Article
  10. Stable structure, shifting links: How depression-anxiety symptom networks reconfigure from pregnancy to postpartum.European psychiatry : the journal of the Association of European Psychiatrists · 2026
    Article
  11. Article
  12. Observational
  13. Article
  14. Article
  15. Review
  16. Article
  17. Review
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  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Lu OuDepartment of Basic Nursing, School of Nursing, Hunan Normal University, Changsha, China.
Quan ShenDepartment of Clinical Nursing, Xiangya Nursing School of Central South University, Changsha, China.
Meili XiaoDepartment of Basic Nursing, School of Nursing, Hunan Normal University, Changsha, China.
Weihong WangDepartment of Basic Nursing, School of Nursing, Hunan Normal University, Changsha, China.
Tan HeDepartment of Clinical Nursing, Xiangya Nursing School of Central South University, Changsha, China.
Binglu WangDepartment of Clinical Nursing, Xiangya Nursing School of Central South University, Changsha, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The prevalence of co-morbid anxiety and depression varies greatly between research studies, making it difficult to understand and estimate the magnitude of this problem. This systematic review and meta-analysis aim to provide up-to-date information on the global prevalence of co-morbid anxiety and depression in pregnant and postpartum women and to further investigate the sources of heterogeneity. Systematic searches of eight electronic databases were conducted for original studies published from inception to December 10, 2024. We selected studies that directly reported prevalence data on co-morbid anxiety and depression during the perinatal periods. We extracted data from published study reports and calculated the pooled prevalence of symptoms of co-morbid anxiety and depression. There are 122 articles involving 560,736 women from 43 different countries included in this review. The global prevalence of co-morbid anxiety and depression during the perinatal period was about 9% (95%CI 8%-10%), with approximately 9% (95%CI 8%-11%) in pregnant women and 8% (95%CI 7%-10%) in postpartum women. Prevalence varied significantly by the assessment time points, study country, study design, and the assessment tool used for anxiety and depression, while prevalence was not dependent on publication year, country income level, and COVID-19 context. No publication bias was observed for this prevalence rate. These findings suggest that approximately 1 in 10 women experience co-morbid anxiety and depression during pregnancy and postpartum. Targeted action is needed to reduce this burden.

Indexed as

AnxietyAnxiety DisordersDepressionDepression, PostpartumPregnancy ComplicationsComorbidityCOVID-19FemaleHumansPostpartum PeriodPregnancyPrevalenceco-morbid anxiety and depressionmeta-analysisperinatalpostpartumpregnancyprevalence

Identifiers

PMID40079080
PMCPMC12080659

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.