Evidence map›Paper›PMID 40078821›Full record

ArticleTransplantation direct2025

Liver Transplant Provider Perspectives on Posttransplant Management of Alcohol Use Disorder.

Maria P Cote, Daniel Cloonan, Sienna Li, Shahaan Razak, Ruby Singh, Taylor Coe, Paula C Zimbrean, Sarah Andrews, Ana Ivkovic, Stephen Bartels and 5 more

Abstract read
In one paragraph

Article in Transplantation direct, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Maria P CoteGroup for Research, education, and the Future of Transplantation (GRaFT), Transplant Surgery Department, Massachusetts General Hospital, Boston, MA.
Daniel CloonanGroup for Research, education, and the Future of Transplantation (GRaFT), Transplant Surgery Department, Massachusetts General Hospital, Boston, MA.ORCID https://orcid.org/0000-0003-2581-2745
Sienna LiGroup for Research, education, and the Future of Transplantation (GRaFT), Transplant Surgery Department, Massachusetts General Hospital, Boston, MA.
Shahaan RazakGroup for Research, education, and the Future of Transplantation (GRaFT), Transplant Surgery Department, Massachusetts General Hospital, Boston, MA.
Ruby SinghGroup for Research, education, and the Future of Transplantation (GRaFT), Transplant Surgery Department, Massachusetts General Hospital, Boston, MA.ORCID https://orcid.org/0000-0003-2664-2338
Taylor CoeGroup for Research, education, and the Future of Transplantation (GRaFT), Transplant Surgery Department, Massachusetts General Hospital, Boston, MA.
Paula C ZimbreanDepartment of Psychiatry and Surgery, Yale School of Medicine, New Haven, CT.
Sarah AndrewsDepartment of Psychiatry, The Johns Hopkins School Medicine, Baltimore, MD.
Ana IvkovicHarvard Medical School, Boston, MA.
Stephen BartelsHarvard Medical School, Boston, MA.ORCID https://orcid.org/0000-0002-7985-2905
Ryan ChadhaDepartment of Anesthesia, Mayo Clinic, Jacksonville, FL.ORCID https://orcid.org/0000-0002-7463-6912
Emily BetheaHarvard Medical School, Boston, MA.ORCID https://orcid.org/0000-0003-3759-8360
Heidi YehGroup for Research, education, and the Future of Transplantation (GRaFT), Transplant Surgery Department, Massachusetts General Hospital, Boston, MA.ORCID https://orcid.org/0000-0002-7379-0600
Nicholas LimDivision of Gastroenterology, Hepatology and Nutrition, University of Minnesota, Minneapolis, MN.ORCID https://orcid.org/0000-0001-9740-8923
Leigh Anne DagefordeGroup for Research, education, and the Future of Transplantation (GRaFT), Transplant Surgery Department, Massachusetts General Hospital, Boston, MA.

Funding

TRAINING IN TRANSPLANTATION BIOLOGYT32AI007529 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI MADSEN, JOREN C · 1998 to 2024
$6.4M
Development and Testing of an Integrated Care Coordination Intervention for Alcohol Use Disorder Recovery after Liver TransplantationK23AA031068 · NIAAA · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Leigh Anne Dageforde · 2023 to 2026
$749k
NIAAA NIH HHS K23 AA031068NIAID NIH HHS T32 AI007529
6 · The paper itself

Abstract

Background: Liver transplantation (LT) is the standard treatment for liver failure secondary to alcohol-associated liver disease, but limited literature and best practices exist for post-LT treatment of alcohol use disorder (AUD). This study explores current AUD management practices and providers' perceived barriers to effective post-LT AUD management. Methods: A 45-item survey on post-LT AUD treatment practices was distributed to members of the American Society of Transplant Surgeons, the Association of Consult/Liaison Psychiatry Transplant Special Interest Group, and both the American Society of Transplantation's Liver and Intestine Community of Practice and Psychosocial and Ethics Community of Practice discussion boards, between December 2021 and April 2022. Univariate analysis of categorical variables was performed using the chi-square test. Data were analyzed using center volume tertiles, country region, and provider professional activity. Results: Two hundred thirty-two respondents from 70 LT centers across all 11 United Network for Organ Sharing regions completed the survey. Half of the them were attending physicians and 16.4% were nurse coordinators. Most centers (84%) aimed for alcohol abstinence for all post-LT patients. Perceived barriers to AUD treatment efficacy included ongoing desire to drink (18%), denial about alcohol misuse (14.9%), and lack of posttransplant support (14%). Additionally, 62.1% of centers had no policy for prescribing medication-assisted therapy to treat AUD, and 32.7% of centers reported no center-level changes in AUD care. Providers identified primary needs as hiring additional mental health professionals (30.8%), dedicating specific staff to AUD care (24.7%), and standardizing psychiatric/psychological care in transplant clinics (17.2%). Conclusions: Despite the increasing volume of LT for alcohol-associated liver disease, significant perceived barriers to effective AUD treatment remain.

Identifiers

PMID40078821
PMCPMC11896101

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.