Evidence map›Paper›PMID 40078247›Full record

ArticleCureus2025

Fluoro-2-Deoxyglucose (FDG)-Avid Adenoid Cystic Carcinoma of the Larynx: A Rare Case and Diagnostic Insight Obtained Using Positron Emission Tomography/Computed Tomography (PET/CT) Imaging.

Serin Moghrabi, Ahmad Al-Muhtaseb, Marwa Y Alshatti, Akram Al-Ibraheem

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Serin MoghrabiNuclear Medicine, King Hussein Cancer Center (KHCC), Amman, JOR.
Ahmad Al-MuhtasebNuclear Medicine, King Hussein Cancer Center (KHCC), Amman, JOR.
Marwa Y AlshattiPathology, King Hussein Cancer Center (KHCC), Amman, JOR.
Akram Al-IbraheemNuclear Medicine, King Hussein Cancer Center (KHCC), Amman, JOR.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Adenoid cystic carcinoma (ACC) is a relatively uncommon tumor among head and neck cancers, with laryngeal involvement, typically subglottic, being exceptionally rare. While ACC usually originates in the salivary glands, its occurrence in the larynx is highly unusual. Laryngeal adenoid cystic carcinoma (LACC) is characterized by indolent growth, frequent perineural invasion, and a tendency for local recurrence. Moreover, distant metastasis can occur with the lungs being the most common site of metastasis. We present a case of a 28-year-old male patient with a progressively enlarging right neck mass, uncovering a rare case of infiltrative LACC invading the thyroid gland. Post thyroidectomy, the 18-fluoro-2-deoxyglucose (F-18-FDG)-positron emission tomography (PET)/computed tomography (CT) scan revealed FDG-avid right posterior subglottic residual disease with invasion into adjacent structures, including the trachea. This represents one of the few documented cases of FDG-avid LACC, contributing to the sparse literature on this rare and aggressive malignancy. This case highlights the diagnostic challenge and clinical significance of FDG-PET/CT in evaluating rare and aggressive malignancies like LACC.

Indexed as

adenoid cystic carcinomafdg pet/ctinvasionlarynxmetastases

Identifiers

PMID40078247
PMCPMC11901416

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.