Evidence map›Paper›PMID 40078228›Full record

ArticleBiosafety and health2023

Simultaneous detection of enterovirus-D68 and vaccine-related poliovirus 3 in the stool samples of a 5-month hospitalized child with acute respiratory disease: A case report.

Wenzhe Su, Qing Zeng, Jinmei Geng, Jingwen Liu, Huaping Xie, Kuibiao Li, Pengzhe Qin, Chaojun Xie, Biao Di

Abstract readCase Reports
In one paragraph

Article in Biosafety and health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Wenzhe SuGuangzhou Center for Disease Control and Prevention, Guangzhou 510000, China.
Qing ZengGuangzhou Center for Disease Control and Prevention, Guangzhou 510000, China.
Jinmei GengGuangzhou Center for Disease Control and Prevention, Guangzhou 510000, China.
Jingwen LiuGuangzhou Center for Disease Control and Prevention, Guangzhou 510000, China.
Huaping XieGuangzhou Center for Disease Control and Prevention, Guangzhou 510000, China.
Kuibiao LiGuangzhou Center for Disease Control and Prevention, Guangzhou 510000, China.
Pengzhe QinGuangzhou Center for Disease Control and Prevention, Guangzhou 510000, China.
Chaojun XieHuadu Center for Disease Control and Prevention, Guangzhou 510803, China.
Biao DiGuangzhou Center for Disease Control and Prevention, Guangzhou 510000, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human enterovirus (EV) infections can lead to various manifestations, with variable correlations between genotypes and symptoms. Human enterovirus D68 (EV-D68) was considered to be associated with acute respiratory disease and acute flaccid myelitis. In this short report, both EV-D68 and poliovirus 3 were detected in the stool of a hospitalized 5-month child who presented with acute respiratory symptoms and who was recently vaccinated with oral polio vaccine (OPV), using a metatranscriptomic high-throughput sequencing method. The nearly full-length genome sequences with complete open reading frames of EV-D68 and poliovirus 3 were assembled. One previously-reported neurovirulence-related amino acid substitution (T860N) in the EV-D68 VP1 region was observed, but the patient showed no neurological symptoms. More attention should be paid to EV-D68, and continuous multiple syndrome-based surveillance on non-polio enterovirus is called for.

Indexed as

Acute respiratory diseaseCo-infectionEnterovirusEV-D68Poliovirus 3Whole genome sequencing

Identifiers

PMID40078228
PMCPMC11895007

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.