ReviewSubstance abuse and rehabilitation2025
Prehospital Use of Medication-Assisted Treatment for Opioid Use Disorder: A Rapid Review of Implementation Approaches and Outcomes.
Review in Substance abuse and rehabilitation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Locations of emergency medical services attended non-fatal opioid-involved overdoses, 888 counties, USA, 2022-2024.Injury prevention : journal of the International Society for Child and Adolescent Injury Prevention · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study aimed to evaluate the use of prehospital medication-assisted treatment (MAT) administration by Emergency Medical Services for opioid use disorder (OUD) through a review of literature published between 2014-2024. A search of the NCBI repository using selected keywords returned N=28 results; articles meeting the inclusion criteria (n=13) were reviewed and analyzed. Heterogeneity among studies was assessed using the Chi-squared test and I² statistic. Studies were categorized into two primary domains: implementation and protocols or patient outcomes. Findings suggest that while MAT administration extends on-scene time, it significantly improves patient retention in OUD treatment. However, operational challenges, including geographical disparities in access and racial inequities in retention, limit widespread implementation. This review underscores the consistent safety of prehospital MAT administration, specifically by EMS personnel outside of an emergency department, yet highlights the need for addressing these barriers to optimize its effectiveness as a critical intervention in managing OUD in the prehospital setting.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.