Evidence map›Paper›PMID 40077853›Full record

ReviewRNA biology2025

Characterization of the binding features between SARS-CoV-2 5'-proximal transcripts of genomic RNA and nucleocapsid proteins.

Shih-Cheng Chen, Cui-Ting Xu, Chuan-Fu Chang, Chia-Shin Yang, Pin-Han Lin, Wei-Min Liu, Yeh Chen, Chien-Hung Yu

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in RNA biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Shih-Cheng ChenNational Institute of Cancer Research, National Health Research Institutes, Tainan City, Taiwan.ORCID 0000-0002-4764-0510
Cui-Ting XuDepartment of Biochemistry and Molecular Biology, College of Medicine, National Cheng Kung University, Tainan City, Taiwan.
Chuan-Fu ChangDepartment of Biochemistry and Molecular Biology, College of Medicine, National Cheng Kung University, Tainan City, Taiwan.
Chia-Shin YangInstitute of Translational Medicine and New Drug Development, College of Medicine, China Medical University, Taichung City, Taiwan.
Pin-Han LinDepartment of Chemistry, Fu Jen Catholic University, New Taipei City, Taiwan.
Wei-Min LiuDepartment of Chemistry, Fu Jen Catholic University, New Taipei City, Taiwan.ORCID 0000-0003-3607-1911
Yeh ChenInstitute of Translational Medicine and New Drug Development, College of Medicine, China Medical University, Taichung City, Taiwan.ORCID 0000-0002-7740-0446
Chien-Hung YuDepartment of Biochemistry and Molecular Biology, College of Medicine, National Cheng Kung University, Tainan City, Taiwan.ORCID 0000-0003-0337-4473

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Packaging signals (PSs) of coronaviruses (CoVs) are specific RNA elements recognized by nucleocapsid (N) proteins that direct the selective packaging of genomic RNAs (gRNAs). These signals have been identified in the coding regions of the nonstructural protein 15 (Nsp 15) in CoVs classified under

Indexed as

Coronavirus Nucleocapsid ProteinsRNA, ViralSARS-CoV-2Viral Genome Packaging5' Untranslated RegionsEndoribonucleasesGenome, ViralPhase SeparationProtein BindingViral Nonstructural ProteinsViral Packaging Sequence5' Untranslated RegionsCoronavirus Nucleocapsid ProteinsEndoribonucleasesnidoviral uridylate-specific endoribonucleaseRNA, ViralViral Nonstructural Proteins5’-UTRscis-acting elementscoronavirusencapsidationN-proteinnucleocapsidRNA structure

Identifiers

PMID40077853
PMCPMC11913385

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.