Evidence map›Paper›PMID 40077758›Full record

SynthesisNutrients2025

Impacts of Yacon Syrup (

Marcos F Pereira, Igor de Codes Soares, Marília Magalhães Cabral, Paula A de Freitas, Gabriel M A Sousa, Saulo Chaves Magalhães, Antônio Augusto Ferreira Carioca, Maria Rayane C de Oliveira, Francisco Ernani A Magalhães, Ariclecio C de Oliveira and 2 more

Abstract readSystematic Review
In one paragraph

Synthesis in Nutrients, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Marcos F PereiraHigher Institute of Biomedical Sciences, State University of Ceara-UECE, Fortaleza 60714-903, CE, Brazil.
Igor de Codes SoaresHigher Institute of Biomedical Sciences, State University of Ceara-UECE, Fortaleza 60714-903, CE, Brazil.ORCID 0009-0008-9430-3446
Marília Magalhães CabralPostgraduate Program in Nutrition and Health, State University of Ceara-UECE, Fortaleza 60714-903, CE, Brazil.ORCID 0000-0002-2076-3721
Paula A de FreitasPostgraduate Program in Nutrition and Health, State University of Ceara-UECE, Fortaleza 60714-903, CE, Brazil.
Gabriel M A SousaHigher Institute of Biomedical Sciences, State University of Ceara-UECE, Fortaleza 60714-903, CE, Brazil.ORCID 0009-0001-7526-6984
Saulo Chaves MagalhãesHigher Institute of Biomedical Sciences, State University of Ceara-UECE, Fortaleza 60714-903, CE, Brazil.
Antônio Augusto Ferreira CariocaDepartment of Nutrition, Postgraduate Studies in Public Health, University of Fortaleza, Fortaleza 60811-905, CE, Brazil.
Maria Rayane C de OliveiraPostgraduate Program in Nutrition and Health, State University of Ceara-UECE, Fortaleza 60714-903, CE, Brazil.
Francisco Ernani A MagalhãesPostgraduate Program in Nutrition and Health, State University of Ceara-UECE, Fortaleza 60714-903, CE, Brazil.ORCID 0000-0002-4924-2882
Ariclecio C de OliveiraHigher Institute of Biomedical Sciences, State University of Ceara-UECE, Fortaleza 60714-903, CE, Brazil.ORCID 0000-0002-9295-8157
Renalison Farias-PereiraDepartment of Biological Sciences, The Dorothy and George Hennings College of Science, Mathematics and Technology, Kean University, Union, NJ 07083, USA.ORCID 0000-0002-8608-2347
Keciany Alves de OliveiraHigher Institute of Biomedical Sciences, State University of Ceara-UECE, Fortaleza 60714-903, CE, Brazil.ORCID 0000-0002-9928-3826

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectivesYacon syrup (

methodsFollowing PRISMA guidelines, we conducted a systematic search in databases, including Medline (PubMed), Science Direct, Embase, Scopus, and SciELO, up to October 2024. Inclusion criteria focused on clinical trials examining the impact of yacon syrup on glycemic control, lipid profile, insulin sensitivity, appetite regulation, and gut microbiota in healthy, overweight, or obese individuals. Seven studies met the inclusion criteria, encompassing 161 participants from diverse populations.

resultsYacon syrup supplementation demonstrated significant reductions in fasting insulin, HOMA-IR, and LDL cholesterol, alongside improvements in satiety and intestinal transit time. Acute supplementation with yacon syrup had inconsistent results for postprandial glycemia and insulin levels, probably due to prior individual gut microbiota composition. Longer interventions with yacon syrup were associated with enhanced microbiota modulation and appetite regulation, particularly in women. Mild gastrointestinal discomfort was reported, but with the continued use of yacon syrup, the symptoms decreased. Yacon syrup presents promising health benefits, including improved insulin sensitivity, weight management, and gut health. However, further research is needed to establish optimal dosing and long-term safety.

conclusionsThis review highlights the potential of yacon syrup as a functional supplement for metabolic and gastrointestinal health.

Indexed as

AsteraceaeAppetiteBlood GlucoseDietary SupplementsFemaleGastrointestinal MicrobiomeHumansInsulinInsulin ResistanceMalePlant ExtractsBlood GlucoseInsulinPlant Extractsyacon syrupdietary supplementsfructooligosaccharidesgut microbiotainsulin sensitivitymetabolic healthsatietysystematic reviewyacon syrup

Identifiers

PMID40077758
PMCPMC11902191

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.