Evidence map›Paper›PMID 40077507›Full record

ReviewFoods (Basel, Switzerland)2025

Clean Label Approaches in Cheese Production: Where Are We?

Jaime Fernandes, Sandra Gomes, Fernando H Reboredo, Manuela E Pintado, Olga Amaral, João Dias, Nuno Alvarenga

Abstract readReview
In one paragraph

Review in Foods (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Mixed Fermentation UsingFoods (Basel, Switzerland) · 2026
    Article
  2. Food preservatives: natural or synthetic?Archives of microbiology · 2026
    Review
  3. Emerging Nonthermal Technologies for the Production of Postbiotics.Comprehensive reviews in food science and food safety · 2025
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jaime FernandesUTI-Unidade de Tecnologia e Inovação, Instituto Nacional de Investigação Agrária e Veterinária IP, Quinta do Marquês, 2780-157 Oeiras, Portugal.ORCID 0000-0002-0505-1443
Sandra GomesUTI-Unidade de Tecnologia e Inovação, Instituto Nacional de Investigação Agrária e Veterinária IP, Quinta do Marquês, 2780-157 Oeiras, Portugal.ORCID 0000-0002-4106-5367
Fernando H ReboredoNOVA School of Science and Technology, Universidade Nova de Lisboa, 2829-516 Caparica, Portugal.ORCID 0000-0002-3906-4349
Manuela E PintadoCBQF-Centro de Biotecnologia e Química Fina, Laboratório Associado, Escola Superior de Biotecnologia, Universidade Católica Portuguesa, Rua Diogo Botelho 1327, 4169-005 Porto, Portugal.ORCID 0000-0002-0760-3184
Olga AmaralGeoBioTec Research Center, NOVA School of Science and Technology, Universidade Nova de Lisboa, 2829-516 Caparica, Portugal.
João DiasGeoBioTec Research Center, NOVA School of Science and Technology, Universidade Nova de Lisboa, 2829-516 Caparica, Portugal.ORCID 0000-0002-5108-0018
Nuno AlvarengaUTI-Unidade de Tecnologia e Inovação, Instituto Nacional de Investigação Agrária e Veterinária IP, Quinta do Marquês, 2780-157 Oeiras, Portugal.ORCID 0000-0003-0625-0687

Funding

EU Recovery and Resilience Plan (PRR), under the project: CASEUS: Combined use of renewable energy sources to improve energy efficiency in cheese industry PRR-C05-i03-I000249FCT-Fundação para a Ciência e a Tecnologia-I.P., under the scope of the research units GeoBioTec Research Centre UIDB/04035/2020
6 · The paper itself

Abstract

The Clean Label concept has gained significant traction in the cheese industry due to consumer preferences for minimally processed cheeses free from synthetic additives. This review explores different approaches for applying Clean Label principles to the cheese industry while maintaining food safety, sensory quality, and shelf life. Non-thermal technologies, such as high-pressure processing (HPP), pulsed electric fields (PEF), ultra-violet (UV), and visible light (VL), are among the most promising methods that effectively control microbial growth while preserving the nutritional and functional properties of cheese. Protective cultures, postbiotics, and bacteriophages represent microbiological strategies that are natural alternatives to conventional preservatives. Another efficient approach involves plant extracts, which contribute to microbial control, and enhance cheese functionality and potential health benefits. Edible coatings, either alone or combined with other methods, also show promising applications. Despite these advantages, several challenges persist: higher costs of production and technical limitations, possible shorter shelf-life, and regulatory challenges, such as the absence of standardized Clean Label definitions and compliance complexities. Further research is needed to develop and refine Clean Label formulations, especially regarding bioactive peptides, sustainable packaging, and advanced microbial control techniques. Addressing these challenges will be essential for expanding Clean Label cheese availability while ensuring product quality and maintaining consumer acceptance.

Indexed as

cheeseclean labeldairy industryedible coatingsfood safetymicrobiological controlnon-thermal processingplant extracts

Identifiers

PMID40077507
PMCPMC11899541

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.