Evidence map›Paper›PMID 40077504›Full record

ArticleFoods (Basel, Switzerland)2025

Antioxidant-Rich Polyfloral Bee Pollen Exerts Antimicrobial Activity and Anti-Inflammatory Effect in A549 Lung Epithelial Cells by Modulating the NF-κB Pathway.

Andrea Cavallero, Francesca Vidotto, Cristiana Sbrana, Laryssa Peres Fabbri, Giulio Petroni, Morena Gabriele

Abstract read
In one paragraph

Article in Foods (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Andrea CavalleroInstitute of Agricultural Biology and Biotechnology, National Research Council, Via Moruzzi 1, 56124 Pisa, Italy.ORCID 0000-0003-3678-7733
Francesca VidottoInstitute of Agricultural Biology and Biotechnology, National Research Council, Via Moruzzi 1, 56124 Pisa, Italy.
Cristiana SbranaInstitute of Agricultural Biology and Biotechnology, National Research Council, Via Moruzzi 1, 56124 Pisa, Italy.ORCID 0000-0002-8058-8566
Laryssa Peres FabbriInstitute of Agricultural Biology and Biotechnology, National Research Council, Via Moruzzi 1, 56124 Pisa, Italy.
Giulio PetroniDepartment of Biology, University of Pisa, Via Luca Ghini 13, 56123 Pisa, Italy.ORCID 0000-0001-9572-9897
Morena GabrieleInstitute of Agricultural Biology and Biotechnology, National Research Council, Via Moruzzi 1, 56124 Pisa, Italy.ORCID 0000-0002-9456-6755

Funding

Ministero dell'università e della ricerca Project code PE00000003, Concession Decree No. 1550 of 11 Octo-ber 2022
6 · The paper itself

Abstract

Bee pollen is produced by honeybees from the agglutination of pollen grains belonging to one or more plant species. Although it is intended to be a nutritional source for the hive, its remarkable concentration of nutrients and phytochemicals, combined with its pleasant organoleptic qualities, makes it appealing for human consumption. This study examined the phytochemical content and the antioxidant and antimicrobial activities of a polyfloral bee pollen collected in Tuscany (Italy). Additionally, its less studied anti-inflammatory potential towards tumor necrosis factor-alpha (TNF-α)-inflamed A549 cells was evaluated to assess its possible use in inflammatory respiratory diseases. Bee pollen extract (BPE) was chemically characterized in terms of total polyphenol (20.2 ± 1.5 mg gallic acid equivalents/g fw), flavonoid (9.22 ± 0.64 mg quercetin equivalents/g fw), and carotenoid (10.4 ± 1.4 µg carotenoids/g fw) contents. BPE exerted good antioxidant and antiradical activities in ferric reducing antioxidant power (38.6 ± 4.5 mg Fe

Indexed as

anti-inflammatory propertiesantimicrobial potentialantioxidant activitybee pollenlung inflammationNF-kB pathwaypolyphenols

Identifiers

PMID40077504
PMCPMC11899311

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.