Evidence map›Paper›PMID 40076958›Full record

ArticleInternational journal of molecular sciences2025

The Impact of SNP Score on Low-Density Lipoprotein Cholesterol Concentration and Coronary Artery Disease.

Darius Čereškevičius, Ieva Čiapienė, Ali Aldujeli, Vytautas Zabiela, Vaiva Lesauskaitė, Kristina Zubielienė, Vytautas Raškevičius, Diana Žaliaduonytė, Ramūnas Unikas, Robertas Pranevičius and 6 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Darius ČereškevičiusInstitute of Cardiology, Lithuanian University of Health Sciences, Sukileliu 15, 50103 Kaunas, Lithuania.
Ieva ČiapienėInstitute of Cardiology, Lithuanian University of Health Sciences, Sukileliu 15, 50103 Kaunas, Lithuania.ORCID 0009-0004-3393-1474
Ali AldujeliInstitute of Cardiology, Lithuanian University of Health Sciences, Sukileliu 15, 50103 Kaunas, Lithuania.ORCID 0000-0002-5567-2221
Vytautas ZabielaInstitute of Cardiology, Lithuanian University of Health Sciences, Sukileliu 15, 50103 Kaunas, Lithuania.ORCID 0000-0002-2761-3996
Vaiva LesauskaitėInstitute of Cardiology, Lithuanian University of Health Sciences, Sukileliu 15, 50103 Kaunas, Lithuania.ORCID 0000-0003-2736-3111
Kristina ZubielienėInstitute of Cardiology, Lithuanian University of Health Sciences, Sukileliu 15, 50103 Kaunas, Lithuania.
Vytautas RaškevičiusInstitute of Cardiology, Lithuanian University of Health Sciences, Sukileliu 15, 50103 Kaunas, Lithuania.ORCID 0000-0002-8448-5951
Diana ŽaliaduonytėDepartment of Cardiology, Kaunas Hospital of the Lithuanian University of Health Sciences, Hipodromo 13, 45130 Kaunas, Lithuania.ORCID 0000-0002-8797-999X
Ramūnas UnikasDepartment of Cardiology, Lithuanian University of Health Sciences, Eivenių 2, 50009 Kaunas, Lithuania.
Robertas PranevičiusInstitute of Cardiology, Lithuanian University of Health Sciences, Sukileliu 15, 50103 Kaunas, Lithuania.
Ignas SimanauskasInstitute of Cardiology, Lithuanian University of Health Sciences, Sukileliu 15, 50103 Kaunas, Lithuania.ORCID 0009-0006-1927-7976
Giedrė BakšytėDepartment of Cardiology, Lithuanian University of Health Sciences, Eivenių 2, 50009 Kaunas, Lithuania.ORCID 0000-0003-4113-004X
Abdonas TamošiūnasInstitute of Cardiology, Lithuanian University of Health Sciences, Sukileliu 15, 50103 Kaunas, Lithuania.ORCID 0000-0002-0868-457X
Dalia LukšienėInstitute of Cardiology, Lithuanian University of Health Sciences, Sukileliu 15, 50103 Kaunas, Lithuania.
Gintarė ŠakalytėInstitute of Cardiology, Lithuanian University of Health Sciences, Sukileliu 15, 50103 Kaunas, Lithuania.
Vacis TatarūnasInstitute of Cardiology, Lithuanian University of Health Sciences, Sukileliu 15, 50103 Kaunas, Lithuania.ORCID 0000-0002-2389-1550

Funding

Lithuanian University of Health Sciences "Mokslo fondas" fund 2024
6 · The paper itself

Abstract

Hypercholesterolemia, characterized by elevated levels of low-density lipoprotein cholesterol (LDL-C), along with inflammation, is a well-known risk factor for developing atherosclerosis and coronary artery disease (CAD). Many patients with hypercholesterolemia may carry inherited genetic variants that are not part of the commonly recognized mutations in the

Indexed as

Cholesterol, LDLCoronary Artery DiseasePolymorphism, Single NucleotideAdultAgedCase-Control StudiesFemaleGenetic Predisposition to DiseaseHumansMaleMiddle AgedMultifactorial InheritancePilot ProjectsRisk FactorsCholesterol, LDLcoronary artery diseasehypercholesterolemialow-density lipoprotein cholesterolPRSSNP score

Identifiers

PMID40076958
PMCPMC11899937

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.