Evidence map›Paper›PMID 40076953›Full record

ArticleInternational journal of molecular sciences2025

HOXA1 Contributes to Bronchial Epithelial Cell Cycle Progression by Regulating p21/CDKN1A.

Elizabeth McCluskey, Sathesh Kanna Velli, Rafal Kaminski, Tyler Markward, Hannah Leming, Daohai Yu, Umadevi Sajjan

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Elizabeth McCluskeyCenter for Inflammation and Lung Research, Lewis-Katz Medical School, Temple University, Philadelphia, PA 19140, USA.
Sathesh Kanna VelliCenter for Inflammation and Lung Research, Lewis-Katz Medical School, Temple University, Philadelphia, PA 19140, USA.
Rafal KaminskiCenter for Neurovirology and Gene Editing, Lewis-Katz Medical School, Temple University, Philadelphia, PA 19140, USA.
Tyler MarkwardCenter for Inflammation and Lung Research, Lewis-Katz Medical School, Temple University, Philadelphia, PA 19140, USA.
Hannah LemingCenter for Inflammation and Lung Research, Lewis-Katz Medical School, Temple University, Philadelphia, PA 19140, USA.
Daohai YuCenter for Biostatistics and Epidemiology, Lewis-Katz Medical School, Temple University, Philadelphia, PA 19140, USA.
Umadevi SajjanCenter for Inflammation and Lung Research, Lewis-Katz Medical School, Temple University, Philadelphia, PA 19140, USA.

Funding

Quercetin prevent airway epithelial remodeling and promote lung health in OPDR01HL157258 · NHLBI · TEMPLE UNIV OF THE COMMONWEALTH · PI SAJJAN, UMADEVI SIVANAPPA · 2021 to 2024
$1.9M
NHLBI NIH HHS R01 HL157258NIH HHS 1R01HL157258-04A1
6 · The paper itself

Abstract

Airway basal cells proliferate and regenerate airway epithelium after injury. The first step during airway epithelial repair is airway basal cell proliferation to close the wound. Previously, we demonstrated that

Indexed as

BronchiCell CycleCyclin-Dependent Kinase Inhibitor p21Epithelial CellsHomeodomain ProteinsTranscription FactorsAnimalsCell LineCell MovementCell ProliferationHomeobox A1 ProteinHumansMiceCyclin-Dependent Kinase Inhibitor p21Homeobox A1 ProteinHomeodomain ProteinsTranscription Factorsairway epithelial repaircell migrationcell proliferationCOPDhomeobox A1

Identifiers

PMID40076953
PMCPMC11899960

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.