Evidence map›Paper›PMID 40076947›Full record

ReviewInternational journal of molecular sciences2025

Use of Natural Biomolecules in Animal Feed to Enhance Livestock Reproduction.

Ikram BenSouf, Mariem Saidani, Asma Maazoun, Bochra Bejaoui, Manel Ben Larbi, Naceur M'Hamdi, Hebib Aggad, Nicolas Joly, Janne Rojas, Marielba Morillo and 1 more

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Impact of Nutrition on Embryo Production in Cattle: Mechanistic Insights.Animals : an open access journal from MDPI · 2026
    Review
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Ikram BenSoufAnimal and Food Resources Laboratory (LRAA), National Agronomic Institute of Tunisia, University of Carthage, 43 Av. Charles Nicolle, Tunis 1082, Tunisia.
Mariem SaidaniResearch Unit of Biodiversity and Resource Development in Mountain Areas of Tunisia, UR17AGR14, Higher School of Agriculture of Mateur, University of Carthage, Tunis 1082, Tunisia.ORCID 0009-0009-9894-4395
Asma MaazounHorticultural Science Laboratory, LR13AGR01, National Agronomic Institute of Tunisia, University of Carthage, 43 Av. Charles Nicolle, Tunis 1082, Tunisia.ORCID 0000-0002-7931-1543
Bochra BejaouiLaboratory of Useful Materials, National Institute of Research and Pysico-Chemical Analysis (INRAP), Technopark of Sidi Thabet, Ariana 2020, Tunisia.ORCID 0000-0002-0009-6247
Manel Ben LarbiResearch Unit of Biodiversity and Resource Development in Mountain Areas of Tunisia, UR17AGR14, Higher School of Agriculture of Mateur, University of Carthage, Tunis 1082, Tunisia.
Naceur M'HamdiAnimal and Food Resources Laboratory (LRAA), National Agronomic Institute of Tunisia, University of Carthage, 43 Av. Charles Nicolle, Tunis 1082, Tunisia.ORCID 0000-0002-9068-3401
Hebib AggadLaboratory of Hygiene and Animal Pathology, Institute of Veterinary Science, University of Tiaret, Route d'Alger BP 78, Tiaret 14000, Algeria.ORCID 0000-0002-3996-4603
Nicolas JolyUnité Transformations &Agroressources, ULR7519, Université d'Artois, UniLaSalle, F-62408 Béthune, France.ORCID 0000-0003-0516-2466
Janne RojasBiomoléculas Orgánicas Research Group, Faculty of Pharmacy and Bioanalysis, University of Los Andes, Mérida 5101, Venezuela.ORCID 0000-0001-5161-6778
Marielba MorilloEcology and Nutrition Research Group, Faculty of Pharmacy and Bioanalysis, University of Los Andes, Mérida 5101, Venezuela.ORCID 0000-0002-6048-0590
Patrick MartinUnité Transformations &Agroressources, ULR7519, Université d'Artois, UniLaSalle, F-62408 Béthune, France.ORCID 0000-0001-7507-5910

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Feed additives are crucial in livestock production, enhancing performance, health, and reproductive efficiency. Recently, there has been a shift toward natural biomolecules as feed additives, specifically targeting improved reproductive outcomes and sperm quality. This transition arises from concerns about antibiotic misuse, antimicrobial resistance, and consumer preferences for eco-friendly products, along with the superior bioavailability, lower toxicity, and reduced environmental impact of natural biomolecules compared to synthetic alternatives. Collaboration among researchers, veterinarians, nutritionists, and regulators is essential to ensure safe and effective livestock management. The review explores advancements in using vital biomolecules in reproductive processes, including plant-derived bioactives such as phytochemicals and antioxidants. It investigates not only the mechanisms but also the intricate interactions of these compounds with animals' hormonal and physiological systems. Additionally, the review critically assesses challenges and prospects related to incorporating natural biomolecules into livestock practices. The potential benefits include enhanced reproductive efficiency and improved sperm quality. However, successful implementation requires understanding factors like precise dosing, potential interactions, and long-term health impacts. Overall, this comprehensive review highlights recent research, technological strides, and the future potential of integrating natural biomolecules into animal diets.

Indexed as

Animal FeedLivestockPhytochemicalsReproductionAnimalsAntioxidantsMaleAntioxidantsPhytochemicalsfeed additiveslivestock reproductionnatural biomoleculessperm quality

Identifiers

PMID40076947
PMCPMC11900002

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.