Evidence map›Paper›PMID 40076945›Full record

ReviewInternational journal of molecular sciences2025

Mercury Exposure and Health Effects: What Do We Really Know?

Angelika Edyta Charkiewicz, Wioleta Justyna Omeljaniuk, Marzena Garley, Jacek Nikliński

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
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  8. A green emitting phenanthroimidazolate anionic room temperature ionic liquid and its low-dimensional materials for ultrasensitive detection of HgPhotochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2026
    Article
  9. Article
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  13. Genetic Polymorphisms and Antioxidant Reactions in Prostate Cancer.International journal of molecular sciences · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Angelika Edyta CharkiewiczDepartment of Clinical Molecular Biology, Medical University of Bialystok, 15-269 Bialystok, Poland.ORCID 0000-0003-2657-454X
Wioleta Justyna OmeljaniukDepartment of Analysis and Bioanalysis of Medicines, Medical University of Bialystok, 15-222 Bialystok, Poland.ORCID 0000-0001-8412-3937
Marzena GarleyDepartment of Immunology, Medical University of Bialystok, 15-269 Bialystok, Poland.ORCID 0000-0002-6727-3850
Jacek NiklińskiDepartment of Clinical Molecular Biology, Medical University of Bialystok, 15-269 Bialystok, Poland.ORCID 0000-0002-8437-1401

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mercury is widely used in medicine, agriculture, and industry. Meanwhile, according to the World Health Organization, it has been ranked as one of the ten most hazardous substances in the world, with the Agency for Toxic Substances and Disease Registry ranking it third. It has no known positive functionality in the human body, and even at low concentrations, it can have harmful long-term health effects, seriously affecting the healthcare system as well as posing a serious public health threat. This review focuses on the health effects of mercury and its major sources in the environment. We highlight its major toxic role in almost every possible aspect. Mercury and its forms, even in the smallest doses, cause numerous disorders to the body, including to the nervous system, the respiratory system, and the cardiovascular system. It can cause disorders such as various cancers; endothelial dysfunction; gastric and vascular disorders; liver, kidney, and brain damage; hormonal imbalances, miscarriages, and reproductive disorders; skin lesions; vision damage; and even death. The fact of such widespread use as well as its toxicity to the human body prompts further and in-depth research in populations of both low and moderate exposure. The constant controlling and monitoring of mercury use is a serious public health problem, requiring urgent attention and attentiveness from the governments of all countries and, in the long run, a rapid and concerted response. Thus, it is important to analyze in depth the impact of this highly toxic metal on the human body and to prepare the most precisely targeted public health interventions among all decision- and policy-makers.

Indexed as

Environmental ExposureEnvironmental PollutantsMercuryAnimalsHumansPublic HealthEnvironmental PollutantsMercuryenvironmental pollutionhealth effectsmercurysourcestoxicity

Identifiers

PMID40076945
PMCPMC11899758

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.