Evidence map›Paper›PMID 40076937›Full record

ReviewInternational journal of molecular sciences2025

Platelet-Rich Plasma and Electrochemical Biosensors: A Novel Approach to Ovarian Function Evaluation and Diagnostics.

Tatjana Ivaskiene, Greta Kaspute, Egle Bareikiene, Urte Prentice

Registry-linked trialAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07376460 (Biological and Proteomic Characterisation of Platelet-rich Plasma), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07376460 not yet recruitingnot on this mapstarted 2026, after this paper: background citation

Biological and Proteomic Characterisation of Platelet-rich Plasma (PRP) Before and After Mobilisation of Haematopoietic Stem Cells in Peripheral Blood From Women With Low Ovarian Response (Low Responders) and in Vitro Evaluation in Human Ovarian Cell Models

TypeobservationalSponsorInstituto Valenciano de Infertilidad, IVI AlicanteRan2026 to 2026Enrolled10ConditionsPoor Ovarian Response, Ovarian ReactivationArmsPlatelet Rich Plasma + BMDSCs mobilization
3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Tatjana IvaskieneState Research Institute Centre for Innovative Medicine, Santariskiu St. 5, LT-08410 Vilnius, Lithuania.ORCID 0000-0003-2064-6792
Greta KasputeState Research Institute Centre for Innovative Medicine, Santariskiu St. 5, LT-08410 Vilnius, Lithuania.ORCID 0009-0002-0605-3317
Egle BareikieneState Research Institute Centre for Innovative Medicine, Santariskiu St. 5, LT-08410 Vilnius, Lithuania.
Urte PrenticeState Research Institute Centre for Innovative Medicine, Santariskiu St. 5, LT-08410 Vilnius, Lithuania.ORCID 0000-0001-6118-3777

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Preserving ovarian function is important to women's reproductive health. It is necessary for fertility and maintaining the overall hormonal balance. Platelet-rich plasma (PRP) is an autologous plasma containing a predominately platelet concentrate prepared from fresh blood. It has been observed that PRP injections into the ovary can renew the functional cells of the cortical layer of the ovary follicles and reactivate the production of sex hormones. It may improve a woman's fertility in the case of premature ovarian failure, the condition after chemotherapy treatment, or during the climacteric period. The main markers to evaluate the procedure's success are elevated anti-Müllerin hormone and enlarged count level of atrial follicles in ovaries. The aim of this review is to identify the ovarian PRP procedure success markers and point out the electrochemical sensor techniques. Literature was selected depending on including and excluding criteria; studies were sorted by topics in two blocks: PRP biomarkers and electrochemistry. As PRP acts as a regenerative care, electrochemical biosensors can provide accurate, real-time data to evaluate the biological response to PRP therapy. The biosensors' ability to monitor hormonal levels and follicle development serves as objective markers of the effectiveness of PRP in restoring ovarian function. Together, these approaches enable a more precise evaluation of ovarian health and fertility outcomes after PRP intervention.

Indexed as

Biosensing TechniquesElectrochemical TechniquesOvaryPlatelet-Rich PlasmaPrimary Ovarian InsufficiencyAnimalsBiomarkersFemaleHumansOvarian FollicleBiomarkersbiomarkersdiagnosiselectrochemistrymolecularly imprinted polymersovarianplatelet-rich plasmaprognosis

Identifiers

PMID40076937
PMCPMC11899975

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.